Editorials:

Pui-Yan Kwok

Finding a Needle in a Haystack: Detection and Quantification of Rare Mutant Alleles Are Coming of Age
Clin Chem 2000 46: 593-594. [Extract] [Full Text] [PDF]  

Reviews:

Martin Burchardt, Tatjana Burchardt, Ahmad Shabsigh, Alexandre De La Taille, Mitchell C. Benson, and Ihor Sawczuk

Current Concepts in Biomarker Technology for Bladder Cancers
Clin Chem 2000 46: 595-605. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Hsien-Hsiung Lee, Jan-Gowth Chang, Chang-Hai Tsai, Fuu-Jen Tsai, Hsiang-Tai Chao, and Bon-chu Chung

Analysis of the Chimeric CYP21P/CYP21 Gene in Steroid 21-Hydroxylase Deficiency
Clin Chem 2000 46: 606-611. [Abstract] [Full Text] [PDF]  

Peter Schadewaldt, Hans-Werner Hammen, Kamalanathan Loganathan, Annette Bodner-Leidecker, and Udo Wendel

Analysis of Concentration and ¹³C Enrichment of D-Galactose in Human Plasma
Clin Chem 2000 46: 612-619. [Abstract] [Full Text] [PDF]  

Caroline J. Fuery, Helen L. Impey, Natalie J. Roberts, Tanya L. Applegate, Robyn L. Ward, Nicholas J. Hawkins, Catherine A. Sheehan, Roslyn O’Grady, and Alison V. Todd

Detection of Rare Mutant Alleles by Restriction Endonuclease-mediated Selective-PCR: Assay Design and Optimization
Clin Chem 2000 46: 620-624. [Abstract] [Full Text] [PDF]  

Alison V. Todd, Caroline J. Fuery, Helen L. Impey, Tanya L. Applegate, and Margaret A. Haughton

DzyNA-PCR: Use of DNAzymes to Detect and Quantify Nucleic Acid Sequences in a Real-Time Fluorescent Format
Clin Chem 2000 46: 625-630. [Abstract] [Full Text] [PDF]  

Juergen Loeffler, Lars Hagmeyer, Holger Hebart, Norbert Henke, Ulrike Schumacher, and Hermann Einsele

Rapid Detection of Point Mutations by Fluorescence Resonance Energy Transfer and Probe Melting Curves in Candida Species
Clin Chem 2000 46: 631-635. [Abstract] [Full Text] [PDF]  

Enzymes and Protein Markers:

Reiko Ishihara, Shigeru Taketani, Misa Sasai-Takedatsu, Yasushi Adachi, Minoru Kino, Akiko Furuya, Nobuo Hanai, Rikio Tokunaga, and Yohnosuke Kobayashi

ELISA for Urinary Trehalase with Monoclonal Antibodies: A Technique for Assessment of Renal Tubular Damage
Clin Chem 2000 46: 636-643. [Abstract] [Full Text] [PDF]  

Klaus Lorentz

Routine -Amylase Assay Using Protected 4-Nitrophenyl-1,4--D-maltoheptaoside and a Novel -Glucosidase
Clin Chem 2000 46: 644-649. [Abstract] [Full Text] [PDF]  

Kristien M. ver Elst, Herbert D. Spapen, Duc Nam Nguyen, Christian Garbar, Luc P. Huyghens, and Frans K. Gorus

Cardiac Troponins I and T Are Biological Markers of Left Ventricular Dysfunction in Septic Shock
Clin Chem 2000 46: 650-657. [Abstract] [Full Text] [PDF]  

Susann Eriksson, Markus Vehniäinen, Tove Jansén, Ville Meretoja, Petri Saviranta, Kim Pettersson, and Timo Lövgren

Dual-Label Time-resolved Immunofluorometric Assay of Free and Total Prostate-specific Antigen Based on Recombinant Fab Fragments
Clin Chem 2000 46: 658-666. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Shaina Hirany, Dawn O’Byrne, Sridevi Devaraj, and Ishwarlal Jialal

Remnant-like Particle-Cholesterol Concentrations in Patients with Type 2 Diabetes Mellitus and End-Stage Renal Disease
Clin Chem 2000 46: 667-672. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Eric S. Lightcap, Teresa A. McCormack, Christine S. Pien, Vincent Chau, Julian Adams, and Peter J. Elliott

Proteasome Inhibition Measurements: Clinical Application
Clin Chem 2000 46: 673-683. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Henning W. Woitge, Heike Oberwittler, Silke Heichel, Andreas Grauer, Reinhard Ziegler, and Markus J. Seibel

Short- and Long-Term Effects of Ibandronate Treatment on Bone Turnover in Paget Disease of Bone
Clin Chem 2000 46: 684-690. [Abstract] [Full Text] [PDF]  

Karin Nilsson, Lars Gustafson, and Björn Hultberg

The Plasma Homocysteine Concentration Is Better Than That of Serum Methylmalonic Acid as a Marker for Sociopsychological Performance in a Psychogeriatric Population
Clin Chem 2000 46: 691-696. [Abstract] [Full Text] [PDF]  

Jean-Hugues Brossard, Raymond Lepage, Héloïse Cardinal, Louise Roy, Louise Rousseau, Claude Dorais, and Pierre D’Amour

Influence of Glomerular Filtration Rate on Non-(1-84) Parathyroid Hormone (PTH) Detected by Intact PTH Assays
Clin Chem 2000 46: 697-703. [Abstract] [Full Text] [PDF]  

Nutrition:

Dinesh Talwar, Helen Davidson, Josephine Cooney, and Denis St. JO’Reilly

Vitamin B₁ Status Assessed by Direct Measurement of Thiamin Pyrophosphate in Erythrocytes or Whole Blood by HPLC: Comparison with Erythrocyte Transketolase Activation Assay
Clin Chem 2000 46: 704-710. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Maria Raffaella Biasin, Tosca Bertin, Giuseppe Sardeo, Paolo Fabris, Enzo Venza, and Domenico Infantolino

Improved Molecular Diagnosis of Hereditary Hemochromatosis Using a DNA Enzyme Immunoassay
Clin Chem 2000 46: 711-712. [Extract] [Full Text] [PDF]  

Rainer P. Woitas, Birgit Stoffel-Wagner, Sabine Flommersfeld, Uwe Poege, Peter Schiedermaier, Hans-Ulrich Klehr, Ulrich Spengler, Frank Bidlingmaier, and Tilman Sauerbruch

Correlation of Serum Concentrations of Cystatin C and Creatinine to Inulin Clearance in Liver Cirrhosis
Clin Chem 2000 46: 712-715. [Extract] [Full Text] [PDF]  

Yan-Yun Wu, Rosario M. Delgado, Trey Sunderland, and Gyorgy Csako

Semiautomated PCR-Single-Strand Conformation Polymorphism Method for Detection of a Novel Sequence Polymorphism (Ile1000Val) in Human ₂-Macroglobulin
Clin Chem 2000 46: 715-718. [Extract] [Full Text] [PDF]  

Farooq Ghani, Alan H.B. Wu, Louis Graff, Christoph Petry, Glenn Armstrong, Florence Prigent, and Milton Brown

Role of Heart-Type Fatty Acid-binding Protein in Early Detection of Acute Myocardial Infarction
Clin Chem 2000 46: 718-719. [Extract] [Full Text] [PDF]  

Else J. Harthoorn-Lasthuizen, Peter van‘t Sant, Jan Lindemans, and Mart M.A.C. Langenhuijsen

Serum Transferrin Receptor and Erythrocyte Zinc Protoporphyrin in Patients with Anemia,
Clin Chem 2000 46: 719-722. [Extract] [Full Text] [PDF]  

Markus Nauck, Michael M. Hoffmann, Heinrich Wieland, and Winfried März

Evaluation of the Apo E Genotyping Kit on the LightCycler,
Clin Chem 2000 46: 722-724. [Extract] [Full Text] [PDF]  

Jong Weon Choi, Moon Whan Im, and Soo Hwan Pai

Serum Transferrin Receptor Concentrations during Normal Pregnancy
Clin Chem 2000 46: 725-727. [Extract] [Full Text] [PDF]  

Robert D. Stevens, Steven L. Hillman, Steven Worthy, Doris Sanders, and David S. Millington

Assay for Free and Total Carnitine in Human Plasma Using Tandem Mass Spectrometry
Clin Chem 2000 46: 727-729. [Extract] [Full Text] [PDF]  

Inge J. van Wijk, Anneke C. de Hoon, Rishma Jurhawan, May Lee Tjoa, Sandra Griffioen, Monique A.M. Mulders, John M.G. van Vugt, and Cees B.M. Oudejans

Detection of Apoptotic Fetal Cells in Plasma of Pregnant Women
Clin Chem 2000 46: 729-731. [Extract] [Full Text] [PDF]  

Véronique Ducros, Monique Ferry, Patrice Faure, Nicole Belin, Jean-Charles Renversez, Daniel Ruffieux, and Alain Favier

Distribution of Selenium in Plasma of French Women: Relation to Age and Selenium Status,
Clin Chem 2000 46: 731-733. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Alessandro Sinicco, Riccardo Raiteri, Antonella Rossati, Andrea Savarino, and Giovanni Di Perri

Efavirenz Interference in Estradiol ELISA Assay
Clin Chem 2000 46: 734-735. [Extract] [Full Text] [PDF]  

Yoshinori Miura, Yoshiyuki Fujimura, Takashi Nishikawa, and Hideki Ohtani

Thiobarbiturates Interfere with the Dade Behring aca Ammonia Test
Clin Chem 2000 46: 735-736. [Extract] [Full Text] [PDF]  

María Luisa Arranz-Peña, Manuel González-Sagrado, Ana María Olmos-Linares, Nuria Fernández-García, and Francisco Javier Martín-Gil

Interference of Iodinated Contrast Media in Serum Capillary Zone Electrophoresis
Clin Chem 2000 46: 736-737. [Extract] [Full Text] [PDF]  

Friedel E. Krapf and Douglas L. Harris

Stability of Clinical Chemistry Analytes in Blood Collection Devices • A representative of Greiner VACUETTE^® North America responds:
Clin Chem 2000 46: 737-738. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Thomas M. Annesley

National Center for Infectious Diseases (NCID). URL: www.cdc.gov/ncidod/
Clin Chem 2000 46: 739. [Extract] [Full Text] [PDF]  

Corrections:

Correction
Clin Chem 2000 46: 739. [Extract] [Full Text] [PDF]  

Clinical Chemistry Forum:

Donald S. Young

Laboratory Automation: Smart Strategies and Practical Applications
Clin Chem 2000 46: 740-745. [Extract] [Full Text] [PDF]  

Charles D. Hawker and Marc R. Schlank

Development of Standards for Laboratory Automation
Clin Chem 2000 46: 746-750. [Abstract] [Full Text] [PDF]  

Richard S. Seaberg, Robert O. Stallone, and Bernard E. Statland

The Role of Total Laboratory Automation in a Consolidated Laboratory Network
Clin Chem 2000 46: 751-756. [Abstract] [Full Text] [PDF]  

Stephen R. Middleton

Developing an Automation Concept That Is Right for Your Laboratory
Clin Chem 2000 46: 757-763. [Abstract] [Full Text] [PDF]  

Rodney S. Markin and Scott A. Whalen

Laboratory Automation: Trajectory, Technology, and Tactics
Clin Chem 2000 46: 764-771. [Abstract] [Full Text] [PDF]  

Sean Graves, Bill Holman, and Robin A. Felder

Modular Robotic Workcell for Coagulation Analysis
Clin Chem 2000 46: 772-777. [Abstract] [Full Text] [PDF]  

Paul J. Orsulak

Stand-Alone Automated Solutions Can Enhance Laboratory Operations
Clin Chem 2000 46: 778-783. [Abstract] [Full Text] [PDF]  

Alexander K. Wing

Laboratory Automation and Optimization: The Role of Architecture
Clin Chem 2000 46: 784-791. [Abstract] [Full Text] [PDF]  

The Clinical Chemist:

Compiled by David E. Bruns, Editor (dbruns@aacc.org) : The Clinical Chemist
Clin Chem 2000 46: 792. [Extract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.