Reviews:

Lynn Bry, Philip C. Chen, and David B. Sacks

Effects of Hemoglobin Variants and Chemically Modified Derivatives on Assays for Glycohemoglobin
Clin Chem 2001 47: 153-163. [Abstract] [Full Text] [PDF]  

Minireview:

Michael M. Shi

Enabling Large-Scale Pharmacogenetic Studies by High-Throughput Mutation Detection and Genotyping Technologies
Clin Chem 2001 47: 164-172. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Huijun Tian, Lawrence C. Brody, Saijun Fan, Zhili Huang, and James P. Landers

Capillary and Microchip Electrophoresis for Rapid Detection of Known Mutations by Combining Allele-specific DNA Amplification with Heteroduplex Analysis
Clin Chem 2001 47: 173-185. [Abstract] [Full Text] [PDF]  

Evelyne Lopez-Crapez, Thierry Livache, Joseph Marchand, and Jean Grenier

K-ras Mutation Detection by Hybridization to a Polypyrrole DNA Chip
Clin Chem 2001 47: 186-194. [Abstract] [Full Text] [PDF]  

Karen E. Bijwaard, Nadine S.I. Aguilera, Yury Monczak, Michel Trudel, Jeffery K. Taubenberger, and Jack H. Lichy

Quantitative Real-Time Reverse Transcription-PCR Assay for Cyclin D1 Expression: Utility in the Diagnosis of Mantle Cell Lymphoma
Clin Chem 2001 47: 195-201. [Abstract] [Full Text] [PDF] Supplemental Table  

Enrico Rossi, Max K. Bulsara, John K. Olynyk, Digby J. Cullen, Lesa Summerville, and Lawrie W. Powell

Effect of Hemochromatosis Genotype and Lifestyle Factors on Iron and Red Cell Indices in a Community Population
Clin Chem 2001 47: 202-208. [Abstract] [Full Text] [PDF]  

Evidence-based Laboratory Medicine and Test Utilization:

James C. Boyd and David E. Bruns

Quality Specifications for Glucose Meters: Assessment by Simulation Modeling of Errors in Insulin Dose
Clin Chem 2001 47: 209-214. [Abstract] [Full Text] [PDF] Supplement  

Enzymes and Protein Markers:

Glen L. Hortin, Ilka Warshawsky, and Maryline Laude-Sharp

Macromolecular Chromogenic Substrates for Measuring Proteinase Activity
Clin Chem 2001 47: 215-222. [Abstract] [Full Text] [PDF]  

Makoto Kawai, Yukichi Hara, Itsuro Miyazato, and Seijin Hosaki

Novel, Aberrantly Truncated Isoform of Serum CD13 in a Family with High Serum Aminopeptidase N (CD13) Activity
Clin Chem 2001 47: 223-230. [Abstract] [Full Text] [PDF]  

Jan M. Andersén, Johan Hedström, Esko Kemppainen, Patrik Finne, and Pauli Puolakkainen

The Ratio of Trypsin-2-₁-Antitrypsin to Trypsinogen-1 Discriminates Biliary and Alcohol-induced Acute Pancreatitis
Clin Chem 2001 47: 231-236. [Abstract] [Full Text] [PDF]  

Liu-Ying Luo, Linda Grass, David J.C. Howarth, Pierre Thibault, Huy Ong, and Eleftherios P. Diamandis

Immunofluorometric Assay of Human Kallikrein 10 and Its Identification in Biological Fluids and Tissues
Clin Chem 2001 47: 237-246. [Abstract] [Full Text] [PDF]  

Birgitte Wuyts, Joris R. Delanghe, Ishmael Kasvosve, Annick Wauters, Hugo Neels, and Jacques Janssens

Determination of Carbohydrate-deficient Transferrin Using Capillary Zone Electrophoresis
Clin Chem 2001 47: 247-255. [Abstract] [Full Text] [PDF]  

Peter H. Tang, Michael V. Miles, Antonius DeGrauw, Andrew Hershey, and Amadeo Pesce

HPLC Analysis of Reduced and Oxidized Coenzyme Q₁₀ in Human Plasma
Clin Chem 2001 47: 256-265. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Daniel M. Hoefner, Shannon D. Hodel, John F. O’Brien, Earl L. Branum, Deborah Sun, Irene Meissner, and Joseph P. McConnell

Development of a Rapid, Quantitative Method for LDL Subfractionation with Use of the Quantimetrix Lipoprint LDL System
Clin Chem 2001 47: 266-274. [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

C. Patrick Case, Lyndon Ellis, Justine C. Turner, and Ben Fairman

Development of a Routine Method for the Determination of Trace Metals in Whole Blood by Magnetic Sector Inductively Coupled Plasma Mass Spectrometry with Particular Relevance to Patients with Total Hip and Knee Arthroplasty
Clin Chem 2001 47: 275-280. [Abstract] [Full Text] [PDF]  

Marie-Paule L.A. Bouche, Jan F.P. Van Bocxlaer, Georges Rolly, Linda F.M. Versichelen, Michel M.R.F. Struys, Eric Mortier, and André P. De Leenheer

Quantitative Determination of Vapor-Phase Compound A in Sevoflurane Anesthesia Using Gas Chromatography–Mass Spectrometry
Clin Chem 2001 47: 281-291. [Abstract] [Full Text] [PDF]  

Rodrigo Aguilera, Thomas E. Chapman, Borislav Starcevic, Caroline K. Hatton, and Don H. Catlin

Performance Characteristics of a Carbon Isotope Ratio Method for Detecting Doping with Testosterone Based on Urine Diols: Controls and Athletes with Elevated Testosterone/Epitestosterone Ratios
Clin Chem 2001 47: 292-300. [Abstract] [Full Text] [PDF]  

Christian Staub, Miguel Marset, Annie Mino, and Patrice Mangin

Detection of Acetylcodeine in Urine as an Indicator of Illicit Heroin Use: Method Validation and Results of a Pilot Study
Clin Chem 2001 47: 301-307. [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Laurence A. Cole, Shohreh Shahabi, Stephen A. Butler, Hugh Mitchell, Edward S. Newlands, Harold R. Behrman, and Harland L. Verrill

Utility of Commonly Used Commercial Human Chorionic Gonadotropin Immunoassays in the Diagnosis and Management of Trophoblastic Diseases
Clin Chem 2001 47: 308-315. [Abstract] [Full Text] [PDF]  

Norman B. Roberts, Alieu B. Amara, Michael Morris, and Brian N. Green

Long-Term Evaluation of Electrospray Ionization Mass Spectrometric Analysis of Glycated Hemoglobin
Clin Chem 2001 47: 316-321. [Abstract] [Full Text] [PDF]  

Laboratory Management:

Patrick J. Parsons, Andrew A. Reilly, Debra Esernio-Jenssen, Lloyd N. Werk, Howard C. Mofenson, Noel V. Stanton, and Thomas D. Matte

Evaluation of Blood Lead Proficiency Testing: Comparison of Open and Blind Paradigms
Clin Chem 2001 47: 322-330. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Georges Gilson, Patrick Schmit, Jean Thix, Jean-Paul Hoffman, and René-Louis Humbel

Prolactin Results for Samples Containing Macroprolactin Are Method and Sample Dependent
Clin Chem 2001 47: 331-333. [Extract] [Full Text] [PDF]  

Georg Endler, Paul A. Kyrle, Sabine Eichinger, Markus Exner, and Christine Mannhalter

Multiplexed Mutagenically Separated PCR: Simultaneous Single-Tube Detection of the Factor V R506Q (G1691A), the Prothrombin G20210A, and the Methylenetetrahydrofolate Reductase A223V (C677T) Variants
Clin Chem 2001 47: 333-335. [Extract] [Full Text] [PDF]  

Chungwen Wei, Devereux N. Saller, and J.W.H. Sutherland

Detection and Quantification by Homogeneous PCR of Cell-free Fetal DNA in Maternal Plasma
Clin Chem 2001 47: 336-338. [Extract] [Full Text] [PDF]  

Hendrik J. Duiser, Freek W.C. Roelandse, Eef G.W.M. Lentjes, Jenny van Loon, John H.M. Souverijn, and Augueste Sturk

Iterative Model for the Calculation of Oxyhemoglobin, Methemoglobin, and Bilirubin in Absorbance Spectra of Cerebrospinal Fluid,
Clin Chem 2001 47: 338-341. [Extract] [Full Text] [PDF]  

Elisabet Miró Casas, Magí Farré Albadalejo, Maria Isabel Covas Planells, Montserrat Fitó Colomer, Rosa M. Lamuela Raventós, and Rafael de la Torre Fornell

Tyrosol Bioavailability in Humans after Ingestion of Virgin Olive Oil
Clin Chem 2001 47: 341-343. [Extract] [Full Text] [PDF]  

Ching-Wan Lam, Priscilla Miu-Kuen Poon, Sui-Fan Tong, Anthony Wing-Ip Lo, Chi-Kong Lai, Kin-Lam Choi, Sau-Cheung Tiu, Yan-Wo Chan, and Chi-Chung Shek

Novel Mutation and Polymorphisms of the HMBS Gene Detected by Denaturing HPLC,
Clin Chem 2001 47: 343-346. [Extract] [Full Text] [PDF]  

Michael J. Diver, David L. Ewins, Richard C. Worth, Shirley Bowles, James A. Ahlquist, and Michael N. Fahie-Wilson

An Unusual Form of Big, Big (Macro) Prolactin in a Pregnant Patient
Clin Chem 2001 47: 346-348. [Extract] [Full Text] [PDF]  

Selma A. Cavalli, Mario H. Hirata, and Rosario D.C. Hirata

Detection of MboII Polymorphism at the 5' Promoter Region of CYP3A4,
Clin Chem 2001 47: 348-351. [Extract] [Full Text] [PDF]  

Xiaolin Yu, Mark M. Thompson, Dashuang Shi, and Mendel Tuchman

Quantification of Benzoic, Phenylacetic, and Phenylbutyric Acids from Filter-Paper Blood Spots by Gas Chromatography–Mass Spectrometry with Stable Isotope Dilution
Clin Chem 2001 47: 351-354. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Franca Pagani and Mauro Panteghini

Biological Variation in Serum Activities of Three Hepatic Enzymes
Clin Chem 2001 47: 355-356. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Jan Lindemans

Point-of-Care Testing. Christopher P. Price, PhD, FRCPath, and Jocelyn M. Hicks, PhD, FRCPath, eds. Washington, DC: AACC Press, 1999, 580 pp., $79.00. ISBN 1-890883-23-9.
Clin Chem 2001 47: 357. [Extract] [Full Text] [PDF]  

Christine Booth

Clinical Nutrition of the Essential Trace Elements and Minerals—The Guide for Health Professionals. John D. Bogden and Leslie M. Klevay, eds. Totowa, NJ: Humana Press, 2000, 380 pp. ISBN 0-89603-407-0.
Clin Chem 2001 47: 357-358. [Extract] [Full Text] [PDF]  

Simon C. Fleming

Liver Disease and Laboratory Medicine. I. McFarlane, A. Bomford, and R. Sherwood. London: ACB Venture Publications, 2000.
Clin Chem 2001 47: 358. [Extract] [Full Text] [PDF]  

James D. Faix

Interpretation of Diagnostic Tests, Seventh Edition. Jacques Wallach. Philadelphia, PA: Lippincott Williams & Wilkins, 2000, 1026 pp., $49.95. ISBN 0-7817-1659-4.
Clin Chem 2001 47: 359. [Extract] [Full Text] [PDF]  

Jose M. Ordovas

Handbook of Lipoprotein Testing, 2nd Edition. Nader Rifai, G. Russell Warnick, Marek H. Dominiczack, eds. Washington DC: AACC Press, 2000, 819 pp. Soft cover, $97.00. ISBN 1-890883-35-2.
Clin Chem 2001 47: 359-360. [Extract] [Full Text] [PDF]  

Abstracts of the 2nd International Symposium on Circulating Nucleic Acids in Plasma and Serum:

The Second International Symposium on Circulating Nucleic Acids in Plasma and Serum (CNAPS-2) held in conjunction with the 6th Annual Scientific Symposium of the Hong Kong Cancer Institute Hong Kong February 20–21, 2001
Clin Chem 2001 47: 361-370. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

Joseph F. Dooley, Robert Emmons, and Joyce Kuhn

History of the Division of Animal Clinical Chemistry: 1974–1983
Clin Chem 2001 47: 371-374. [Extract] [Full Text] [PDF]  

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