Editorials:

Michael W. Steffes and David B. Sacks

Measurement of Circulating Glucose Concentrations: The Time Is Now for Consistency among Methods and Types of Samples
Clin Chem 2005 51: 1569-1570. [Extract] [Full Text] [PDF]  

O. John Semmes

The "omics" Haystack: Defining Sources of Sample Bias in Expression Profiling
Clin Chem 2005 51: 1571-1572. [Extract] [Full Text] [PDF]  

Special Reports:

Paul D’Orazio, Robert W. Burnett, Niels Fogh-Andersen, Ellis Jacobs, Katsuhiko Kuwa, Wolf R. Külpmann, Lasse Larsson, Andrzej Lewenstam, Anton H.J. Maas, Gerhard Mager, Jerzy W. Naskalski, Anthony O. Okorodudu the International Federation of Clinical Chemistry Scientific Division Working Group on Selective Electrodes and Point of Care Testing

Approved IFCC Recommendation on Reporting Results for Blood Glucose (Abbreviated)
Clin Chem 2005 51: 1573-1576. [Abstract] [Full Text] [PDF]  

Reviews:

Christopher P. Price, Ronald G. Newall, and James C. Boyd

Use of Protein:Creatinine Ratio Measurements on Random Urine Samples for Prediction of Significant Proteinuria: A Systematic Review
Clin Chem 2005 51: 1577-1586. Published online July 14, 2005; 10.1373/clinchem.2005.049742 [Abstract] [Full Text] [PDF]  

Cathy M. McHugh, Roderick T. Park, Peter H. Sönksen, and Richard I.G. Holt

Challenges in Detecting the Abuse of Growth Hormone in Sport
Clin Chem 2005 51: 1587-1593. Published online July 14, 2005; 10.1373/clinchem.2005.047845 [Abstract] [Full Text] [PDF]  

Opinion:

Mauro Panteghini

Standardization of Cardiac Troponin I Measurements: The Way Forward?
Clin Chem 2005 51: 1594-1597. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Bernhard Zimmermann, Ahmad El-Sheikhah, Kypros Nicolaides, Wolfgang Holzgreve, and Sinuhe Hahn

Optimized Real-Time Quantitative PCR Measurement of Male Fetal DNA in Maternal Plasma
Clin Chem 2005 51: 1598-1604. Published online July 14, 2005; 10.1373/clinchem.2005.051235 [Abstract] [Full Text] [PDF] Data Supplements  

Stéphanie Gofflot, Manuel Deprez, Benaïssa el Moualij, Awad Osman, Jean-François Thonnart, Olivier Hougrand, Ernst Heinen, and Willy Zorzi

Immunoquantitative PCR for Prion Protein Detection in Sporadic Creutzfeldt–Jakob Disease
Clin Chem 2005 51: 1605-1611. Published online July 7, 2005; 10.1373/clinchem.2005.050120 [Abstract] [Full Text] [PDF]  

Katarzyna Gromek and Tadeusz Kaczorowski

DNA Sequencing by Indexer Walking
Clin Chem 2005 51: 1612-1618. Published online July 21, 2005; 10.1373/clinchem.2004.046599 [Abstract] [Full Text] [PDF] Data Supplement  

Alison Millson, Genevieve Pont-Kingdon, Sam Page, and Elaine Lyon

Direct Molecular Haplotyping of the IVS-8 Poly(TG) and PolyT Repeat Tracts in the Cystic Fibrosis Gene by Melting Curve Analysis of Hybridization Probes
Clin Chem 2005 51: 1619-1623. Published online July 14, 2005; 10.1373/clinchem.2005.052159 [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Erik J. Mulder, Alida Oosterloo-Duinkerken, George M. Anderson, Elisabeth G.E. De Vries, Ruud B. Minderaa, and Ido P. Kema

Automated On-Line Solid-Phase Extraction Coupled with HPLC for Measurement of 5-Hydroxyindole-3-acetic Acid in Urine
Clin Chem 2005 51: 1698-1703. Published online July 14, 2005; 10.1373/clinchem.2005.050062 [Abstract] [Full Text] [PDF]  

Tibor Görögh, Pierre Rudolph, Jens Eduard Meyer, Jochen A. Werner, Burkard M. Lippert, and Steffen Maune

Separation of ß₂-Transferrin by Denaturing Gel Electrophoresis to Detect Cerebrospinal Fluid in Ear and Nasal Fluids
Clin Chem 2005 51: 1704-1710. Published online July 14, 2005; 10.1373/clinchem.2005.054916 [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Talin Gulesserian, Catharina Wenzel, Georg Endler, Raute Sunder-Plassmann, Claudia Marsik, Christine Mannhalter, Nelly Iordanova, Mariann Gyöngyösi, Johann Wojta, Stefan Mustafa, Oswald Wagner, and Kurt Huber

Clinical Restenosis after Coronary Stent Implantation Is Associated with the Heme Oxygenase-1 Gene Promoter Polymorphism and the Heme Oxygenase-1 +99G/C Variant
Clin Chem 2005 51: 1661-1665. Published online July 14, 2005; 10.1373/clinchem.2005.051581 [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Guillaume Hoizey, Denis Lamiable, Thierry Trenque, Arnaud Robinet, Laurent Binet, Matthieu L. Kaltenbach, Sandrine Havet, and Hervé Millart

Identification and Quantification of 8 Sulfonylureas with Clinical Toxicology Interest by Liquid Chromatography–Ion-Trap Tandem Mass Spectrometry and Library Searching
Clin Chem 2005 51: 1666-1672. Published online July 14, 2005; 10.1373/clinchem.2005.050864 [Abstract] [Full Text] [PDF]  

Evidence-Based Laboratory Medicine and Test Utilization:

Martin Möckel, Reinhold Müller, Jörn O. Vollert, Christian Müller, Angelika Carl, Dirk Peetz, Felix Post, J. Klaus Kohse, and Karl J. Lackner

Role of N-Terminal Pro-B-Type Natriuretic Peptide in Risk Stratification in Patients Presenting in the Emergency Room
Clin Chem 2005 51: 1624-1631. [Abstract] [Full Text] [PDF]  

Gunn B.B. Kristensen, Nina Gade Christensen, Geir Thue, and Sverre Sandberg

Between-Lot Variation in External Quality Assessment of Glucose: Clinical Importance and Effect on Participant Performance Evaluation
Clin Chem 2005 51: 1632-1636. [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Rosamonde E. Banks, Anthea J. Stanley, David A. Cairns, Jennifer H. Barrett, Paul Clarke, Douglas Thompson, and Peter J. Selby

Influences of Blood Sample Processing on Low–Molecular-Weight Proteome Identified by Surface-Enhanced Laser Desorption/Ionization Mass Spectrometry
Clin Chem 2005 51: 1637-1649. Published online July 7, 2005; 10.1373/clinchem.2005.051417 [Abstract] [Full Text] [PDF] Data Supplements  

Hugo Vanderstichele, Geert De Meyer, Niels Andreasen, Vesna Kostanjevecki, Anders Wallin, Annika Olsson, Kaj Blennow, and Eugeen Vanmechelen

Amino-Truncated ß-Amyloid₄₂ Peptides in Cerebrospinal Fluid and Prediction of Progression of Mild Cognitive Impairment
Clin Chem 2005 51: 1650-1660. Published online July 14, 2005; 10.1373/clinchem.2005.051201 [Abstract] [Full Text] [PDF] Data Supplements  

Endocrinology and Metabolism:

Anna Michno, Anna Raszeja-Specht, Agnieszka Jankowska-Kulawy, Tadeusz Pawelczyk, and Andrzej Szutowicz

Effect of L-Carnitine on Acetyl-CoA Content and Activity of Blood Platelets in Healthy and Diabetic Persons
Clin Chem 2005 51: 1673-1682. Published online July 14, 2005; 10.1373/clinchem.2005.050328 [Abstract] [Full Text] [PDF]  

Zoë Maunsell, Dennis J. Wright, and Sandra J. Rainbow

Routine Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry Assay for Simultaneous Measurement of the 25-Hydroxy Metabolites of Vitamins D₂ and D₃
Clin Chem 2005 51: 1683-1690. Published online July 14, 2005; 10.1373/clinchem.2005.052936 [Abstract] [Full Text] [PDF]  

Dimitrios Panidis, Christos Balaris, Dimitrios Farmakiotis, David Rousso, Anargyros Kourtis, Vassilios Balaris, Ilias Katsikis, Vassiliki Zournatzi, and Evanthia Diamanti-Kandarakis

Serum Parathyroid Hormone Concentrations Are Increased in Women with Polycystic Ovary Syndrome
Clin Chem 2005 51: 1691-1697. Published online July 21, 2005; 10.1373/clinchem.2005.052761 [Abstract] [Full Text] [PDF]  

Technical Briefs:

Christian Timmann, Florian Moenkemeyer, Jennifer A. Evans, Birgit Foerster, Egbert Tannich, Sylvia Haase, Juergen Sievertsen, Elisabeth Kohne, and Rolf D. Horstmann

Diagnosis of ⁺-Thalassemias by Determining the Ratio of the Two -Globin Gene Copies by Oligonucleotide Hybridization and Melting Curve Analysis
Clin Chem 2005 51: 1711-1713. [Extract] [Full Text] [PDF]  

Donald R. Warden and Helga Refsum

Detection of Single-Nucleotide Polymorphisms by PCR with Universal Energy Transfer–Labeled Primers: Application to Folate- and Cobalamin-Related Genes
Clin Chem 2005 51: 1713-1716. Published online July 21, 2005; 10.1373/clinchem.2004.045195 [Extract] [Full Text] [PDF] Data Supplements  

Marion Funk, Renate Freitag, Georg Endler, Wolfgang Lalouschek, Wilfried Lang, Christine Mannhalter, and Raute Sunder-Plassmann

Influence of Cytochrome P450 2C9*2 and 2C9*3 Variants on the Risk of Ischemic Stroke: A Cross-sectional Case–Control Study
Clin Chem 2005 51: 1716-1718. [Extract] [Full Text] [PDF]  

Katrin M. Kirschbaum, Matthias J. Müller, Gerald Zernig, Alois Saria, Arian Mobascher, Jaroslav Malevani, and Christoph Hiemke

Therapeutic Monitoring of Aripiprazole by HPLC with Column-Switching and Spectrophotometric Detection
Clin Chem 2005 51: 1718-1721. [Extract] [Full Text] [PDF] Supplemental Data  

GholamAli Khoschsorur

Simultaneous Measurement of Sirolimus and Everolimus in Whole Blood by HPLC with Ultraviolet Detection
Clin Chem 2005 51: 1721-1724. [Extract] [Full Text] [PDF]  

Elena Rossou, Anastasia Kouvatsi, Charalampos Aslanidis, and Constantinos Deltas

Multiplex Molecular Diagnosis of MEFV Mutations in Patients with Familial Mediterranean Fever by LightCycler Real-Time PCR
Clin Chem 2005 51: 1725-1727. [Extract] [Full Text] [PDF]  

Anders Helander and Helen Dahl

Urinary Tract Infection: A Risk Factor for False-Negative Urinary Ethyl Glucuronide but Not Ethyl Sulfate in the Detection of Recent Alcohol Consumption
Clin Chem 2005 51: 1728-1730. [Extract] [Full Text] [PDF]  

Xiao Yan Zhong, Stefan Gebhardt, Renate Hillermann, Kashefa Carelse Tofa, Wolfgang Holzgreve, and Sinuhe Hahn

Parallel Assessment of Circulatory Fetal DNA and Corticotropin-Releasing Hormone mRNA in Early- and Late-Onset Preeclampsia
Clin Chem 2005 51: 1730-1733. [Extract] [Full Text] [PDF]  

Courtney Holmes, Jeffrey Moak, Basil Eldadah, Ella Zimmerly, Yehonatan Sharabi, and David S. Goldstein

Dopamine Contamination of Infused Tyramine
Clin Chem 2005 51: 1733-1735. Published online July 21, 2005; 10.1373/clinchem.2005.054361 [Extract] [Full Text] [PDF]  

Jian-Jun Li and Chun-Hong Fang

Effects of 4 Weeks of Atorvastatin Administration on the Antiinflammatory Cytokine Interleukin-10 in Patients with Unstable Angina
Clin Chem 2005 51: 1735-1738. [Extract] [Full Text] [PDF]  

Michele M. Flanders, Ronda A. Crist, William L. Roberts, and George M. Rodgers

Pediatric Reference Intervals for Seven Common Coagulation Assays
Clin Chem 2005 51: 1738-1742. [Extract] [Full Text] [PDF]  

Jiyuan Zhao, Qionglin Liang, Guoan Luo, Yiming Wang, Yanjia Zuo, Ming Jiang, Guilan Yu, and Ting Zhang

Purine Metabolites in Gout and Asymptomatic Hyperuricemia: Analysis by HPLC–Electrospray Tandem Mass Spectrometry
Clin Chem 2005 51: 1742-1744. [Extract] [Full Text] [PDF] Data Supplements  

P. Marc van der Zee, Hein J. Verberne, Jan P. van Straalen, Gerard T.B. Sanders, Berthe L.F. Van Eck-Smit, Robbert J. de Winter, and Johan C. Fischer

Ischemia-Modified Albumin Measurements in Symptom-Limited Exercise Myocardial Perfusion Scintigraphy Reflect Serum Albumin Concentrations but Not Myocardial Ischemia
Clin Chem 2005 51: 1744-1746. [Extract] [Full Text] [PDF]  

Johan Schiettecatte, Anne Van Opdenbosch, Ellen Anckaert, Jean De Schepper, Kris Poppe, Brigitte Velkeniers, and Johan Smitz

Immunoprecipitation for Rapid Detection of Macroprolactin in the Form of Prolactin–Immunoglobulin Complexes
Clin Chem 2005 51: 1746-1748. Published online July 7, 2005; 10.1373/clinchem.2005.048504 [Extract] [Full Text] [PDF] Data Supplement  

Letters to the Editor:

Marion Challier, Sophie Jacqueminet, Ouardia Benabdesselam, André Grimaldi, and Jean-Louis Beaudeux

Increased Serum Concentrations of Soluble Receptor for Advanced Glycation Endproducts in Patients with Type 1 Diabetes
Clin Chem 2005 51: 1749-1750. [Extract] [Full Text] [PDF]  

Dorothy B. Colagiovanni, Dennis J. Meyer, Julie M. Wolf, Karen Hart, Elizabeth Abbott, and Corrie Santos

High -Glutamyltransferase (GGT) Activity in Human Breast Milk Confounds Interpretation of High Serum GGT Activity in a Nursing Infant with Liver Disease
Clin Chem 2005 51: 1750-1751. [Extract] [Full Text] [PDF]  

Masakazu Izumi, Jinko Ishikawa, Akihiro Takeshita, and Masato Maekawa

Increased Serum Alkaline Phosphatase Activity Originating from Neutrophilic Leukocytes
Clin Chem 2005 51: 1751-1752. [Extract] [Full Text] [PDF]  

Norbert Ostendorf, Thomas Glosemeyer-Allhoff, Katrin Schauerte, and Raina Yamamoto

Hemoglobin (Hb) Stanleyville II Causes Gross Overestimation of the Hb A_1c Proportion in Routine HPLC
Clin Chem 2005 51: 1752-1754. [Extract] [Full Text] [PDF]  

Na Na, Jin Ouyang, Youri E.C. Taes, and Joris R. Delanghe

Serum Free Hemoglobin Concentrations in Healthy Individuals Are Related to Haptoglobin Type
Clin Chem 2005 51: 1754-1755. [Extract] [Full Text] [PDF]  

Susann Eriksson and Kim Pettersson

Beliefs in Cardiac Troponin Testing
Clin Chem 2005 51: 1755-1756. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Erasmus Schneider

Cancer Diagnostics: Current and Future Trends. Robert M. Nakamura, Wayne W. Grody, James T. Wu, and Raymond B. Nagle, editors. Totowa, NJ: Humana Press, Inc., 2004, 520 pp., $165.00, hardcover. ISBN 1-58829-167-7.
Clin Chem 2005 51: 1757-1758. [Extract] [Full Text] [PDF]  

Susan Neill

The Hitchhiker’s Guide to Effective Time Management, 2nd ed. Christopher S. Frings. Washington, DC: AACC Press, 2004, 112 pp., $25.00 ($20.00 AACC members), softcover. ISBN 1-5942-003-0.
Clin Chem 2005 51: 1758. [Extract] [Full Text] [PDF]  

Marcia Eisenberg

DNA: Forensic and Legal Applications. Lawrence Kobilinsky, Thomas F. Liotti, and Jamel Oeser-Sweat. Hoboken, NJ: John Wiley & Sons, Inc., 2005, 364 pp., hardcover, $89.95. ISBN 0-471-41478-6.
Clin Chem 2005 51: 1759. [Extract] [Full Text] [PDF]  

Corrections:

Correction for Volume 51, Issue , p. 1232
Clin Chem 2005 51: 1759. [Extract] [Full Text] [PDF]  

Correction for Volume 51, Issue , p. 603
Clin Chem 2005 51: 1759. [Extract] [Full Text] [PDF]  

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