Editorials:

Udo Reischl

Melting of the Ribosomal RNA Gene Reveals Bacterial Species Identity: A Step toward a New Rapid Test in Clinical Microbiology
Clin Chem 2006 52: 1985-1987. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Jakob Stenman, Annukka Paju, Oso Rissanen, Tuomas Tenkanen, Caj Haglund, Jari Räsänen, Jarmo Salo, Ulf-Håkan Stenman, and Arto Orpana

Targeted Gene-Expression Analysis by Genome-Controlled Reverse Transcription-PCR
Clin Chem 2006 52: 1988-1996. Published online September 21, 2006; 10.1373/clinchem.2006.073064 [Abstract] [Full Text] [PDF] 073064.Supplemental Data Table 1  

Ju-Chien Cheng, Chien-Ling Huang, Chung-Ching Lin, Chi-Ching Chen, Yi-Chih Chang, Shy-Shin Chang, and Ching-Ping Tseng

Rapid Detection and Identification of Clinically Important Bacteria by High-Resolution Melting Analysis after Broad-Range Ribosomal RNA Real-Time PCR
Clin Chem 2006 52: 1997-2004. Published online September 21, 2006; 10.1373/clinchem.2006.069286 [Abstract] [Full Text] [PDF] 069286.Supplemental Data  

Mircea Schneider, Franziska Joncourt, Javier Sanz, Thomas von Känel, and Sabina Gallati

Detection of Exon Deletions within an Entire Gene (CFTR) by Relative Quantification on the LightCycler
Clin Chem 2006 52: 2005-2012. Published online September 21, 2006; 10.1373/clinchem.2005.065136 [Abstract] [Full Text] [PDF] 065136.Supplemental Data  

Gyula Richárd Nagy, Balázs Gyõrffy, Orsolya Galamb, Béla Molnár, Bálint Nagy, and Zoltán Papp

Use of Routinely Collected Amniotic Fluid for Whole-Genome Expression Analysis of Polygenic Disorders
Clin Chem 2006 52: 2013-2020. Published online September 28, 2006; 10.1373/clinchem.2006.074971 [Abstract] [Full Text] [PDF] 074971.Supplemental Data  

Hillary H. Hegener, I-Min Lee, Nancy R. Cook, Paul M. Ridker, and Robert Y.L. Zee

Association of Adiponectin Gene Variations with Risk of Incident Myocardial Infarction and Ischemic Stroke: A Nested Case-Control Study
Clin Chem 2006 52: 2021-2027. Published online September 21, 2006; 10.1373/clinchem.2006.074476 [Abstract] [Full Text] [PDF] 074476.Supplemental Data  

Evidence-Based Laboratory Medicine and Test Utilization:

Peter A. Kavsak, Andrew R. MacRae, Glenn E. Palomaki, Alice M. Newman, Dennis T. Ko, Viliam Lustig, Jack V. Tu, and Allan S. Jaffe

Health Outcomes Categorized by Current and Previous Definitions of Acute Myocardial Infarction in an Unselected Cohort of Troponin-Naïve Emergency Department Patients
Clin Chem 2006 52: 2028-2035. Published online September 21, 2006; 10.1373/clinchem.2006.073403 [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Shiming Zhu, Guohai Su, and Qing H. Meng

Inhibitory Effects of Micronized Fenofibrate on Carotid Atherosclerosis in Patients with Essential Hypertension
Clin Chem 2006 52: 2036-2042. Published online September 21, 2006; 10.1373/clinchem.2006.074724 [Abstract] [Full Text] [PDF]  

Gabriella Pepe, Guglielmina Chimienti, Grazia Maria Liuzzi, Biagia Leila Lamanuzzi, Marina Nardulli, Francesco Lolli, Eduardo Anglés-Cano, and Sabrina Matà

Lipoprotein(a) in the Cerebrospinal Fluid of Neurological Patients with Blood–Cerebrospinal Fluid Barrier Dysfunction
Clin Chem 2006 52: 2043-2048. Published online September 21, 2006; 10.1373/clinchem.2006.073544 [Abstract] [Full Text] [PDF]  

Mitsuyo Okazaki, Shinichi Usui, Akio Fukui, Isao Kubota, and Hitonobu Tomoike

Component Analysis of HPLC Profiles of Unique Lipoprotein Subclass Cholesterols for Detection of Coronary Artery Disease
Clin Chem 2006 52: 2049-2053. Published online September 21, 2006; 10.1373/clinchem.2006.070094 [Abstract] [Full Text] [PDF] 070094.Supplemental Data  

Angelo Zinellu, Elisabetta Zinellu, Salvatore Sotgia, Marilena Formato, Gian Mario Cherchi, Luca Deiana, and Ciriaco Carru

Factors Affecting S-Homocysteinylation of LDL Apoprotein B
Clin Chem 2006 52: 2054-2059. Published online September 21, 2006; 10.1373/clinchem.2006.071142 [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Keith L. Brain, Jonathan Kay, and Brian Shine

Measurement of Urinary Metanephrines to Screen for Pheochromocytoma in an Unselected Hospital Referral Population
Clin Chem 2006 52: 2060-2064. Published online September 21, 2006; 10.1373/clinchem.2006.070805 [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Hua Wang, Yun Zhang, Bani Yan, Li Liu, Shiping Wang, Guoli Shen, and Ruqin Yu

Rapid, Simple, and Sensitive Immunoagglutination Assay with SiO₂ Particles and Quartz Crystal Microbalance for Quantifying Schistosoma japonicum Antibodies
Clin Chem 2006 52: 2065-2071. Published online September 21, 2006; 10.1373/clinchem.2006.071555 [Abstract] [Full Text] [PDF] 071555.Supplemental Data  

Laboratory Management:

Alexandra Dorn-Beineke, Parviz Ahmad-Nejad, Ulrike Pfeiffer, Simon Ramsden, Mario Pazzagli, and Michael Neumaier

Improvement of Technical and Analytical Performance in DNA Sequencing by External Quality Assessment-Based Molecular Training
Clin Chem 2006 52: 2072-2078. Published online September 21, 2006; 10.1373/clinchem.2006.072405 [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Annette Zoeger, Michael Blau, Karl Egerer, Eugen Feist, and Burkhardt Dahlmann

Circulating Proteasomes Are Functional and Have a Subtype Pattern Distinct from 20S Proteasomes in Major Blood Cells
Clin Chem 2006 52: 2079-2086. Published online September 21, 2006; 10.1373/clinchem.2006.072496 [Abstract] [Full Text] [PDF]  

Peter A. Benn, Gregory S. Makowski, James F.X. Egan, and Dave Wright

Reproducibility of Risk Figures in 2nd-Trimester Maternal Serum Screening for Down Syndrome: Comparison of 2 Laboratories
Clin Chem 2006 52: 2087-2094. Published online September 21, 2006; 10.1373/clinchem.2006.068783 [Abstract] [Full Text] [PDF]  

Pediatric Clinical Chemistry:

Maria Weyermann, Christopher Beermann, Hermann Brenner, and Dietrich Rothenbacher

Adiponectin and Leptin in Maternal Serum, Cord Blood, and Breast Milk
Clin Chem 2006 52: 2095-2102. Published online September 21, 2006; 10.1373/clinchem.2006.071019 [Abstract] [Full Text] [PDF]  

Technical Briefs:

Ali Bouamrani, Jessica Ternier, David Ratel, Alim-Louis Benabid, Jean-Paul Issartel, Elisabeth Brambilla, and François Berger

Direct-Tissue SELDI-TOF Mass Spectrometry Analysis: A New Application for Clinical Proteomics
Clin Chem 2006 52: 2103-2106. Published online September 21, 2006; 10.1373/clinchem.2006.070979 [Abstract] [Full Text] [PDF] 070979.Supplemental Data  

Case Reports:

Raffick A.R. Bowen, Steven K. Drake, Rachna Vanjani, Edward D. Huey, Jordan Grafman, and McDonald K. Horne, III

Markedly Increased Vitamin B₁₂ Concentrations Attributable to IgG–IgM–Vitamin B₁₂ Immune Complexes
Clin Chem 2006 52: 2107-2114. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Radomir Pilny, Pavel Bouchal, Sarka Borilova, Pavla Ceskova, Jan Zaloudik, Rostislav Vyzula, Borivoj Vojtesek, and Dalibor Valik

Surface-Enhanced Laser Desorption Ionization/Time-of-Flight Mass Spectrometry Reveals Significant Artifacts in Serum Obtained from Clot Activator–Containing Collection Devices
Clin Chem 2006 52: 2115-2116. [Extract] [Full Text] [PDF]  

Chao Lin and James K. Tusa

Equimolar Ammonia Interference in Potassium Measurement on the Osmetech OPTI CCA: A Reply
Clin Chem 2006 52: 2116-2117. [Extract] [Full Text] [PDF]  

Dai Xinhua

Preparation of Uric Acid Standard Stock Solution
Clin Chem 2006 52: 2117-2118. [Extract] [Full Text] [PDF]  

Deirdré Hartman, Timothy W. Doulton, Christine A. Chesters, Giuseppe A. Sagnella, and Graham A. MacGregor

Plasma Aldosterone: Comparison of a New Automated Assay with a Standard Extraction Method
Clin Chem 2006 52: 2118-2119. [Extract] [Full Text] [PDF]  

Joshua A. Bornhorst, Roxann Cousin, Auono T. Pili, J. Alan Erickson, and Edward R. Ashwood

Evaluation of the Efficacy of Chloroform Extraction of Amniotic Fluid Bilirubin
Clin Chem 2006 52: 2120-2121. [Extract] [Full Text] [PDF]  

Jan S. Krouwer

More on Reporting Medical Errors
Clin Chem 2006 52: 2120. [Extract] [Full Text] [PDF]  

Kiyonori Miura, Koh-ichiro Yoshiura, Shoko Miura, Kentaro Yamasaki, Daisuke Nakayama, Tadayuki Ishimaru, Joseph Wagstaff, Norio Niikawa, and Hideaki Masuzaki

Cell-Free DNA Is More Sensitive than Cell-Free mRNA as a Marker for Evaluation of Fetal-Maternal Hemorrhage
Clin Chem 2006 52: 2121-2123. [Extract] [Full Text] [PDF]  

Maciej Adamczyk, R. Jeffrey Brashear, and Phillip G. Mattingly

Choline Concentration in Normal Blood Donor and Cardiac Troponin–Positive Plasma Samples
Clin Chem 2006 52: 2123-2124. [Extract] [Full Text] [PDF]  

Neil Binkley, Marc K. Drezner, and Bruce W. Hollis

Laboratory Reporting of 25-Hydroxyvitamin D Results: Potential for Clinical Misinterpretation
Clin Chem 2006 52: 2124-2125. [Extract] [Full Text] [PDF]  

Carine Garcia-Hejl, Philippe Vest, Christophe Renard, Audrey Merens-Gonthier, Abderrahaman Boukhira, and Helene Thefenne-Astier

Falsely Low LDL Cholesterol Results and Cholestasis
Clin Chem 2006 52: 2125-2127. [Extract] [Full Text] [PDF] 072249. Supplemental Data  

Nathalie Hézard, Marie-Geneviève Remy, Bernadette Florent, and Philippe Nguyen

Reliability of Thrombin Generation Assay on Frozen-Thawed Platelet-Rich Plasma: A Reply
Clin Chem 2006 52: 2127-2128. [Extract] [Full Text] [PDF]  

Oak Ridge Conference:

Steven C. Kazmierczak, Andrey Gurachevsky, Gert Matthes, and Vladimir Muravsky

Electron Spin Resonance Spectroscopy of Serum Albumin: A Novel New Test for Cancer Diagnosis and Monitoring
Clin Chem 2006 52: 2129-2134. Published online September 21, 2006; 10.1373/clinchem.2006.073148 [Abstract] [Full Text] [PDF]  

Ming Zhao, David Nolte, Wonryeon Cho, Fred Regnier, Manoj Varma, Greg Lawrence, and John Pasqua

High-Speed Interferometric Detection of Label-Free Immunoassays on the Biological Compact Disc
Clin Chem 2006 52: 2135-2140. Published online September 21, 2006; 10.1373/clinchem.2006.072793 [Abstract] [Full Text] [PDF]  

Owen T.M. Chan and David A. Herold

Chip Electrophoresis as a Method for Quantifying Total Microalbuminuria
Clin Chem 2006 52: 2141-2146. Published online September 21, 2006; 10.1373/clinchem.2006.072801 [Abstract] [Full Text] [PDF]  

Abstracts of Oak Ridge Posters:

Lawrence A. Haff, Christopher G.M. Wilson, Yumei Huang, Benjamin K. Benton, Julian F Bond, Andrew M. Stern, Richard F. Begley, and James M. Coull

DNA-Programmed Chemistry in Rapid Homogeneous Assays for DNA and Protein Targets
Clin Chem 2006 52: 2147-2148. [Extract] [Full Text] [PDF]  

Ling Huang and Matthew A. Cooper

Real-Time Label-Free Acoustic Technology for Rapid Detection of Escherichia coli O157:H7
Clin Chem 2006 52: 2148-2151. [Extract] [Full Text] [PDF]  

Maria Magliulo, Barbara Roda, Andrea Zattoni, Elisa Michelini, Mirella Luciani, Rossella Lelli, Pierluigi Reschiglian, and Aldo Roda

An Innovative, Flow-Assisted, Noncompetitive Chemiluminescent Immunoassay for the Detection of Pathogenic Bacteria,
Clin Chem 2006 52: 2151-2155. [Extract] [Full Text] [PDF] 072579.Supplementary Data  

N. Babic, T.S. Larson, S.K. Grebe, S.T. Turner, R. Kumar, and R.J. Singh

Application of Liquid Chromatography–Mass Spectrometry Technology for Early Detection of Microalbuminuria in Patients with Kidney Disease
Clin Chem 2006 52: 2155-2157. [Extract] [Full Text] [PDF]  

Alan H.B. Wu, Noelle Fukushima, Robert Puskas, John Todd, and Philippe Goix

Development and Preliminary Clinical Validation of a High Sensitivity Assay for Cardiac Troponin Using a Capillary Flow (Single Molecule) Fluorescence Detector
Clin Chem 2006 52: 2157-2159. [Extract] [Full Text] [PDF]  

Judith A. Finlay, Eric W. Klee, Cari McDonald, John R. Attewell, Deanne Hebrink, Roy Dyer, Brad Love, George Vasmatzis, Thomas M. Li, Joseph M. Beechem, and George G. Klee

A Systematic Method for Selection of Promising Serum Protein Biomarkers to Improve Prostate Cancer (PCa¹) Detection
Clin Chem 2006 52: 2159-2162. [Extract] [Full Text] [PDF]  

Eric W. Klee, Judith A. Finlay, Cari McDonald, John R. Attewell, Deanne Hebrink, Roy Dyer, Brad Love, George Vasmatzis, Thomas M. Li, Joseph M. Beechem, and George G. Klee

Bioinformatics Methods for Prioritizing Serum Biomarker Candidates
Clin Chem 2006 52: 2162-2164. [Extract] [Full Text] [PDF]  

Gregory D. Sgarlato and Howard H. Sussman

Representational Fragment Amplification: Exponential Amplification of Fragmented cDNA Enables Multimillion-Fold Expression Testing
Clin Chem 2006 52: 2164-2168. [Extract] [Full Text] [PDF]  

Vitali Borisenko, Wei Hu, Pui Tam, Irene Chen, Jean-François Houle, and Walter Ausserer

Diffractive Optics Technology: A Novel Detection Technology for Immunoassays
Clin Chem 2006 52: 2168-2170. [Extract] [Full Text] [PDF]  

Roger B. Peck, Johannes Schweizer, Bernhard H. Weigl, Chamorro Somoza, Jon Silver, John W. Sellors, and Peter S. Lu

A Magnetic Immunochromatographic Strip Test for Detection of Human Papillomavirus 16 E6
Clin Chem 2006 52: 2170-2172. [Extract] [Full Text] [PDF]  

Eric A. Nalefski, Christina M. D’Antoni, Evan P. Ferrell, Janice A. Lloyd, Haoqun Qiu, John L. Harris, and Duncan H. Whitney

Single-Molecule Detection for Femtomolar Quantification of Proteins in Heterogeneous Immunoassays
Clin Chem 2006 52: 2172-2175. [Extract] [Full Text] [PDF] 072850.Supplemental Data  

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