Editorials:

Alan Shenkin

Serum Prealbumin: Is It a Marker of Nutritional Status or of Risk of Malnutrition?
Clin Chem 2006 52: 2177-2179. [Extract] [Full Text] [PDF]  

Mark Brantly

Efficient and Accurate Approaches to the Laboratory Diagnosis of 1-Antitrypsin Deficiency: The Promise of Early Diagnosis and Intervention
Clin Chem 2006 52: 2180-2181. [Extract] [Full Text] [PDF]  

Diana W. Bianchi

Will Epigenetic Allelic Ratio Analysis Turn Prenatal Diagnosis of Trisomy 18 on Its EAR?
Clin Chem 2006 52: 2182-2183. [Extract] [Full Text] [PDF]  

Point/Counterpoint:

Petrie M. Rainey

Automatic Reporting of Estimated Glomerular Filtration Rate—Jumping the Gun?
Clin Chem 2006 52: 2184-2187. Published online October 26, 2006; 10.1373/clinchem.2006.069732 [Extract] [Full Text] [PDF]  

Andrew S. Levey, Lesley A. Stevens, and Thomas Hostetter

Automatic Reporting of Estimated Glomerular Filtration Rate—Just What the Doctor Ordered
Clin Chem 2006 52: 2188-2193. Published online October 26, 2006; 10.1373/clinchem.2006.078733 [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Yu K. Tong, Chunming Ding, Rossa W.K. Chiu, Ageliki Gerovassili, Stephen S.C. Chim, Tak Y. Leung, Tse N. Leung, Tze K. Lau, Kypros H. Nicolaides, and Y.M. Dennis Lo

Noninvasive Prenatal Detection of Fetal Trisomy 18 by Epigenetic Allelic Ratio Analysis in Maternal Plasma: Theoretical and Empirical Considerations
Clin Chem 2006 52: 2194-2202. Published online October 13, 2006; 10.1373/clinchem.2006.076851 [Abstract] [Full Text] [PDF] Data Supplement  

Chia-Cheng Hung, Chih-Ping Chen, Shuan-Pei Lin, Shu-Chin Chien, Chien-Nan Lee, Wen-Fang Cheng, Wu-Shiun Hsieh, Ming S. Liu, Yi-Ning Su, and Win-Li Lin

Quantitative Assay of Deletion or Duplication Genotype by Capillary Electrophoresis System: Application in Prader–Willi Syndrome and Duchenne Muscular Dystrophy
Clin Chem 2006 52: 2203-2210. Published online October 13, 2006; 10.1373/clinchem.2006.071118 [Abstract] [Full Text] [PDF] Data Supplement  

K.C. Allen Chan, Chunming Ding, Ageliki Gerovassili, Sze W. Yeung, Rossa W.K. Chiu, Tse N. Leung, Tze K. Lau, Stephen S.C. Chim, Grace T.Y. Chung, Kypros H. Nicolaides, and Y.M. Dennis Lo

Hypermethylated RASSF1A in Maternal Plasma: A Universal Fetal DNA Marker that Improves the Reliability of Noninvasive Prenatal Diagnosis
Clin Chem 2006 52: 2211-2218. Published online October 26, 2006; 10.1373/clinchem.2006.074997 [Abstract] [Full Text] [PDF] Data Supplements  

Evidence-Based Laboratory Medicine and Test Utilization:

Carl van Walraven, Geta Cernat, and Peter C. Austin

Effect of Provider Continuity on Test Repetition
Clin Chem 2006 52: 2219-2228. Published online October 19, 2006; 10.1373/clinchem.2006.072934 [Abstract] [Full Text] [PDF]  

Joël Coste, Patrick Jourdain, and Jacques Pouchot

A Gray Zone Assigned to Inconclusive Results of Quantitative Diagnostic Tests: Application to the Use of Brain Natriuretic Peptide for Diagnosis of Heart Failure in Acute Dyspneic Patients
Clin Chem 2006 52: 2229-2235. Published online October 19, 2006; 10.1373/clinchem.2006.072280 [Abstract] [Full Text] [PDF]  

Melissa R. Snyder, Jerry A. Katzmann, Malinda L. Butz, Ping Yang, D. Brian Dawson, Kevin C. Halling, W. Edward Highsmith, and Stephen N. Thibodeau

Diagnosis of -1-Antitrypsin Deficiency: An Algorithm of Quantification, Genotyping, and Phenotyping
Clin Chem 2006 52: 2236-2242. Published online October 19, 2006; 10.1373/clinchem.2006.072991 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Joachim Kuhn, Christian Prante, Sylvia Schön, Christian Götting, and Knut Kleesiek

Measurement of Fibrosis Marker Xylosyltransferase I Activity by HPLC Electrospray Ionization Tandem Mass Spectrometry
Clin Chem 2006 52: 2243-2249. Published online October 13, 2006; 10.1373/clinchem.2006.071167 [Abstract] [Full Text] [PDF] Data Supplement  

Cancer Diagnostics:

Angela Tan, David Westerman, Grant A. McArthur, Kevin Lynch, Paul Waring, and Alexander Dobrovic

Sensitive Detection of KIT D816V in Patients with Mastocytosis
Clin Chem 2006 52: 2250-2257. Published online October 13, 2006; 10.1373/clinchem.2006.068205 [Abstract] [Full Text] [PDF] Data Supplement  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Glen L. Hortin, Nitin Seam, and Gerard T. Hoehn

Bound Homocysteine, Cysteine, and Cysteinylglycine Distribution between Albumin and Globulins
Clin Chem 2006 52: 2258-2264. Published online October 26, 2006; 10.1373/clinchem.2006.074302 [Abstract] [Full Text] [PDF] Data Supplement  

Jing Cao, Kerry A. Schwichtenberg, Naomi Q. Hanson, and Michael Y. Tsai

Incorporation and Clearance of Omega-3 Fatty Acids in Erythrocyte Membranes and Plasma Phospholipids
Clin Chem 2006 52: 2265-2272. Published online October 19, 2006; 10.1373/clinchem.2006.072322 [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Yang Luo, Ming Chen, Qianjun Wen, Meng Zhao, Bo Zhang, Xiaoyan Li, Feng Wang, Qing Huang, Chunyan Yao, Tianlun Jiang, Guoru Cai, and Weiling Fu

Rapid and Simultaneous Quantification of 4 Urinary Proteins by Piezoelectric Quartz Crystal Microbalance Immunosensor Array
Clin Chem 2006 52: 2273-2280. Published online October 19, 2006; 10.1373/clinchem.2006.073569 [Abstract] [Full Text] [PDF] Supplemental Data  

Nutrition:

Gianluigi Devoto, Fabrizio Gallo, Concetta Marchello, Omar Racchi, Roberta Garbarini, Stefano Bonassi, Giorgio Albalustri, and Enrico Haupt

Prealbumin Serum Concentrations as a Useful Tool in the Assessment of Malnutrition in Hospitalized Patients
Clin Chem 2006 52: 2281-2285. Published online October 26, 2006; 10.1373/clinchem.2006.080366 [Abstract] [Full Text] [PDF]  

Case Conference:

Lorin M. Henrich, Alan D. Rogol, Pierre D’Amour, Michael A. Levine, John B. Hanks, and David E. Bruns

Persistent Hypercalcemia After Parathyroidectomy in an Adolescent and Effect of Treatment With Cinacalcet HCl
Clin Chem 2006 52: 2286-2293. Published online November 14, 2006; 10.1373/clinchem.2006.070219 [Abstract] [Full Text] [PDF]  

Technical Briefs:

Frédérique Vernel-Pauillac and Fabrice Merien

A Novel Real-Time Duplex PCR Assay for Detecting penA and ponA Genotypes in Neisseria gonorrhoeae: Comparison with Phenotypes Determined by the E-Test
Clin Chem 2006 52: 2294-2296. Published online October 19, 2006; 10.1373/clinchem.2006.075309 [Abstract] [Full Text] [PDF]  

Brian G. Keevil and Susan Thornton

Quantification of Urinary Oxalate by Liquid Chromatography–Tandem Mass Spectrometry with Online Weak Anion Exchange Chromatography
Clin Chem 2006 52: 2296-2299. Published online October 13, 2006; 10.1373/clinchem.2006.075275 [Abstract] [Full Text] [PDF] Data Supplement  

Lisa Kann, James Han, David Ahlquist, Theodore Levin, Douglas Rex, Duncan Whitney, Sanford Markowitz, and Anthony Shuber

Improved Marker Combination for Detection of De Novo Genetic Variation and Aberrant DNA in Colorectal Neoplasia
Clin Chem 2006 52: 2299-2302. Published online November 2, 2006; 10.1373/clinchem.2007.070896 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Noh Jin Park, Tianwei Yu, Vishad Nabili, Brigitta M.N. Brinkman, Sharon Henry, Jianghua Wang, and David T. Wong

RNAprotect Saliva: An Optimal Room- Temperature Stabilization Reagent for the Salivary Transcriptome
Clin Chem 2006 52: 2303-2304. [Extract] [Full Text] [PDF]  

Jane A. Schmidt

Measurement of 25-Hydroxyvitamin D Revisited
Clin Chem 2006 52: 2304-2305. [Extract] [Full Text] [PDF]  

Gary Lensmeyer, Donald Wiebe, Neil Binkley, and Marc Drezner

The authors of the article cited above respond:
Clin Chem 2006 52: 2305-2306. [Extract] [Full Text] [PDF]  

Etienne C.H.J. Michielsen, Jart H.C. Diris, Will K.W.H. Wodzig, and Marja P. Van Dieijen-Visser

Size-Exclusion Chromatography of Circulating Cardiac Troponin T
Clin Chem 2006 52: 2306-2307. [Extract] [Full Text] [PDF]  

Michael N. Fahie-Wilson, Elizabeth M. Hall, and Edmund J. Lamb

The authors of the article cited above respond:
Clin Chem 2006 52: 2307-2309. [Extract] [Full Text] [PDF]  

Pieter Vermeersch, Godelieve Mariën, and Xavier Bossuyt

A Case of Pseudoparaproteinemia on Capillary Zone Electrophoresis Caused by Geloplasma
Clin Chem 2006 52: 2309-2311. [Extract] [Full Text] [PDF]  

Ying Li, Wolfgang Holzgreve, Vivian Kiefer, and Sinuhe Hahn

MALDI-TOF Mass Spectrometry Compared With Real-Time PCR for Detection of Fetal Cell-Free DNA in Maternal Plasma
Clin Chem 2006 52: 2311-2312. [Extract] [Full Text] [PDF]  

Pieter Vermeersch, Godelieve Mariën, and Xavier Bossuyt

Pseudoparaproteinemia Related to Iomeprol Administration after Angiocardiography: Detection in the ß Fraction by Capillary Zone Electrophoresis
Clin Chem 2006 52: 2312-2313. [Extract] [Full Text] [PDF]  

Vincent Gajdos, François M. Petit, Claire Perret, Alix Mollet–Boudjemline, Patrice Colin, Liliane Capel, Viviane Nicaud, Alun Evans, Dominique Arveiler, Frédéric Parisot, Jeanne Francoual, Emmanuelle Genin, François Cambien, and Philippe Labrune

Further Evidence That the UGT1A1*28 Allele Is Not Associated with Coronary Heart Disease: The ECTIM Study
Clin Chem 2006 52: 2313-2314. [Extract] [Full Text] [PDF]  

Corrections:

Correction
Clin Chem 2006 52: 2315-2318. [Extract] [Full Text] [PDF]  

Obituary:

John Savory and Kent E. Opheim

Obituary: Alex Kaplan PhD (1910 – 2006)
Clin Chem 2006 52: 2319-2320. [Extract] [Full Text] [PDF]  

The Clinical Chemist:

David E. Bruns

The Clinical Chemist
Clin Chem 2006 52: 2321-2322. [Extract] [Full Text] [PDF]  

Invited Reviewers:

Invited Reviewers—2006
Clin Chem 2006 52: 2323-2326. [Extract] [Full Text] [PDF]  

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