Perspective:

Shahram Shahangian, Kathleen M. LaBeau, and Devery A. Howerton

Prothrombin Time Testing Practices: Adherence to Guidelines and Standards
Clin Chem 2006 52: 793-794. [Extract] [Full Text] [PDF]  

Editorials:

Joseph S. Alpert

Will the Real Myocardial Infarction Please Stand Up?
Clin Chem 2006 52: 795-796. [Extract] [Full Text] [PDF]  

Tobias Pischon and Eric B. Rimm

Adiponectin: A Promising Marker for Cardiovascular Disease
Clin Chem 2006 52: 797-799. [Extract] [Full Text] [PDF]  

Review:

Wenqing Cao and Yixiang Duan

Breath Analysis: Potential for Clinical Diagnosis and Exposure Assessment
Clin Chem 2006 52: 800-811. Published online March 2, 2006; 10.1373/clinchem.2005.063545 [Abstract] [Full Text] [PDF]  

Evidence-Based Laboratory Medicine and Test Utilization:

Andrew R. MacRae, Peter A. Kavsak, Viliam Lustig, Rakesh Bhargava, Rudy Vandersluis, Glenn E. Palomaki, Marie-Jeanne Yerna, and Allan S. Jaffe

Assessing the Requirement for the 6-Hour Interval between Specimens in the American Heart Association Classification of Myocardial Infarction in Epidemiology and Clinical Research Studies
Clin Chem 2006 52: 812-818. Published online March 23, 2006; 10.1373/clinchem.2005.059550 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Diego Gazzolo, Emanuela Marinoni, Romolo Di Iorio, Mario Lituania, Mauro Marras, Matteo Bruschettini, Pierluigi Bruschettini, Rosanna Frulio, Fabrizio Michetti, Felice Petraglia, and Pasquale Florio

High Maternal Blood S100B Concentrations in Pregnancies Complicated by Intrauterine Growth Restriction and Intraventricular Hemorrhage
Clin Chem 2006 52: 819-826. Published online March 16, 2006; 10.1373/clinchem.2005.060665 [Abstract] [Full Text] [PDF]  

Alfons Gegenhuber, Joachim Struck, Werner Poelz, Richard Pacher, Nils G. Morgenthaler, Andreas Bergmann, Meinhard Haltmayer, and Thomas Mueller

Midregional Pro-A-Type Natriuretic Peptide Measurements for Diagnosis of Acute Destabilized Heart Failure in Short-of-Breath Patients: Comparison with B-Type Natriuretic Peptide (BNP) and Amino-Terminal proBNP
Clin Chem 2006 52: 827-831. Published online March 16, 2006; 10.1373/clinchem.2005.065441 [Abstract] [Full Text] [PDF]  

Stefan James, Mats Flodin, Nina Johnston, Bertil Lindahl, and Per Venge

The Antibody Configurations of Cardiac Troponin I Assays May Determine Their Clinical Performance
Clin Chem 2006 52: 832-837. Published online March 16, 2006; 10.1373/clinchem.2005.064857 [Abstract] [Full Text] [PDF]  

Cancer Diagnostics:

Timo Piironen, Alexander Haese, Hartwig Huland, Thomas Steuber, Ib Jarle Christensen, Nils Brünner, Keld Danø, Gunilla Høyer-Hansen, and Hans Lilja

Enhanced Discrimination of Benign from Malignant Prostatic Disease by Selective Measurements of Cleaved Forms of Urokinase Receptor in Serum
Clin Chem 2006 52: 838-844. Published online March 16, 2006; 10.1373/clinchem.2005.064253 [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Ronit Calderon-Margalit, Bella Adler, Joseph H. Abramson, Jaime Gofin, and Jeremy D. Kark

Butyrylcholinesterase Activity, Cardiovascular Risk Factors, and Mortality in Middle-Aged and Elderly Men and Women in Jerusalem
Clin Chem 2006 52: 845-852. Published online March 9, 2006; 10.1373/clinchem.2005.059857 [Abstract] [Full Text] [PDF]  

Maximilian von Eynatten, Andreas Hamann, Dorothee Twardella, Peter P. Nawroth, Hermann Brenner, and Dietrich Rothenbacher

Relationship of Adiponectin with Markers of Systemic Inflammation, Atherogenic Dyslipidemia, and Heart Failure in Patients with Coronary Heart Disease
Clin Chem 2006 52: 853-859. Published online March 23, 2006; 10.1373/clinchem.2005.060509 [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Antoon J.M. Janssen, Frans J.M. Trijbels, Rob C.A. Sengers, Liesbeth T.M. Wintjes, Wim Ruitenbeek, Jan A.M. Smeitink, Eva Morava, Baziel G.M. van Engelen, Lambert P. van den Heuvel, and Richard J.T. Rodenburg

Measurement of the Energy-Generating Capacity of Human Muscle Mitochondria: Diagnostic Procedure and Application to Human Pathology
Clin Chem 2006 52: 860-871. Published online March 16, 2006; 10.1373/clinchem.2005.062414 [Abstract] [Full Text] [PDF]  

Eduard Rogatsky, Beate Balent, Gayotri Goswami, Vlad Tomuta, Harsha Jayatillake, Greg Cruikshank, Louis Vele, and Daniel T. Stein

Sensitive Quantitative Analysis of C-Peptide in Human Plasma by 2-Dimensional Liquid Chromatography–Mass Spectrometry Isotope-Dilution Assay
Clin Chem 2006 52: 872-879. Published online March 23, 2006; 10.1373/clinchem.2005.063081 [Abstract] [Full Text] [PDF] 063081.Supplemental Data  

General Clinical Chemistry:

Graham Ross Dallas Jones

Effect of the Reporting-Interval Size on Critical Difference Estimation: Beyond "2.77"
Clin Chem 2006 52: 880-885. Published online March 2, 2006; 10.1373/clinchem.2005.063107 [Abstract] [Full Text] [PDF]  

Technical Briefs:

Yasumasa Iwasaki, Hiroyuki Matsuyama, and Nobuo Nakashima

Improved Specificity of a New Homogeneous Assay for LDL-Cholesterol in Serum with Abnormal Lipoproteins
Clin Chem 2006 52: 886-888. Published online March 23, 2006; 10.1373/clinchem.2005.053983 [Abstract] [Full Text] [PDF] 053983.Supplemental Data  

Michael Weber, Birgitt Rabenau, Michael Stanisch, Albrecht Elsaesser, Vesselin Mitrovic, Christopher Heeschen, and Christian Hamm

Influence of Sample Type and Storage Conditions on Soluble CD40 Ligand Assessment
Clin Chem 2006 52: 888-891. Published online March 9, 2006; 10.1373/clinchem.2005.062083 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Sihe Wang, Virginia Ho, Altheia Roquemore-Goins, and Frederick A. Smith

Effects of Blood Collection Tubes, including Pediatric Devices, on 16 Common Immunoassays
Clin Chem 2006 52: 892-893. [Extract] [Full Text] [PDF]  

Barbara Laika, Stefan Leucht, and Werner Steimer

ABCB1 (P-Glycoprotein/MDR1) Gene G2677T/A Sequence Variation (Polymorphism): Lack of Association with Side Effects and Therapeutic Response in Depressed Inpatients Treated with Amitriptyline
Clin Chem 2006 52: 893-895. [Extract] [Full Text] [PDF]  

Wojciech Gernand

How Reliable Are Critical Error Calculations?
Clin Chem 2006 52: 895-896. [Extract] [Full Text] [PDF]  

Steven Rossi, Tony Yaksh, Heather Bentley, Geoffrey van den Brande, Igor Grant, and Ronald Ellis

Characterization of Interference with 6 Commercial ⁹-Tetrahydrocannabinol Immunoassays by Efavirenz (Glucuronide) in Urine
Clin Chem 2006 52: 896-897. [Extract] [Full Text] [PDF]  

Christa Meisinger, Berthold Koletzko, and Joachim Heinrich

Metabolic Syndrome: Older than Usually Assumed, But Still Too Young to Die
Clin Chem 2006 52: 897-898. [Extract] [Full Text] [PDF]  

Gerald M. Reaven

The Metabolic Syndrome: What’s in a Name? Reply to: Meisinger et al. Metabolic Syndrome: Older than Usually Assumed, But Still Too Young to Die
Clin Chem 2006 52: 898-899. [Extract] [Full Text] [PDF]  

Marina Gorrini, Ilaria Ferrarotti, Anna Lupi, Tiziana Bosoni, Paola Mazzola, Roberta Scabini, Ilaria Campo, Michele Zorzetto, Francesco Novazi, and Maurizio Luisetti

Validation of a Rapid, Simple Method to Measure ₁-Antitrypsin in Human Dried Blood Spots
Clin Chem 2006 52: 899-901. [Extract] [Full Text] [PDF] Data Supplement 062059.Supplemental Data  

Krisztina Alapi, Melinda Erdos, Olga Török, and László Maródi

Prenatal Diagnosis of the WAS R86H Sequence Variation in Heterozygous Twins
Clin Chem 2006 52: 901-903. [Extract] [Full Text] [PDF]  

Nina Ljungdahl, Mathias Haarhaus, Cecilia Linder, and Per Magnusson

Comparison of 3 Third-Generation Assays for Bio-intact Parathyroid Hormone
Clin Chem 2006 52: 903-904. [Extract] [Full Text] [PDF]  

Xavier Cussonneau, Magali Bolon-Larger, and Roselyne Boulieu

Adsorption of Mycophenolic Acid and Its Phenolic Glucuronide to Glass, Polystyrene, and Polypropylene Containers
Clin Chem 2006 52: 904-906. [Extract] [Full Text] [PDF] Data Supplements  

Nathan Lueck and Yash Pal Agrawal

Lack of Utility of Free Light Chain–Specific Antibodies in the Urine Immunofixation Test
Clin Chem 2006 52: 906-907. [Extract] [Full Text] [PDF]  

Jean-Yves Hautem, Claire Morel, Rémy Couderc, and Fathi Moussa

Liquid Chromatographic Determination of B₂ Vitamers in Human Plasma and Whole Blood
Clin Chem 2006 52: 907-908. [Extract] [Full Text] [PDF] Supplemental Data 065920.Supplemental Data  

Corrections:

Correction
Clin Chem 2006 52: 909. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

R You Using R?
Clin Chem 2006 52: 910. [Extract] [Full Text] [PDF]  

Data Analysis and Graphics Using R. An Example-based Approach. John Maindonald and John Braun. New York: Cambridge University Press, 2003, reprinted 2005, 385 pp., $75.00, hardcover. ISBN 0-521-81336-0. (Book web sites: http://www.stats.uwo.ca/DAAG and http://www.maths.anu.edu.au/~johnm/r-book.html).
Clin Chem 2006 52: 910. [Extract] [Full Text] [PDF]  

A. Ralph Henderson

Statistics. An Introduction using R. Michael J Crawley. Hoboken, NJ: John Wiley & Sons, Inc., 2005, 335 pp. $130.00, hardcover. ISBN 0-470-02297-3, $44.95; paperback. ISBN 0-470-02298-1. (Book web site: http://www.imperial.ac.uk/lifesciences/research/statisticsusingr).
Clin Chem 2006 52: 910-911. [Extract] [Full Text] [PDF]  

Richard W. Jenny

Drugs of Abuse, Body Fluid Testing. Raphael C. Wong and Harley Y. Tse, editors. Totowa, NJ: Humana Press, 2005, 305 pp., $145.00, hardcover. ISBN 1-58829-435-8.
Clin Chem 2006 52: 911-912. [Extract] [Full Text] [PDF]  

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