Editorials:

David J. Pettitt and Lois Jovanovic

Do We Know How to Find Gestational Diabetes Mellitus?
Clin Chem 2006 52: 1633-1634. [Extract] [Full Text] [PDF]  

Nader Rifai and Robert E. Gerszten

Biomarker Discovery and Validation
Clin Chem 2006 52: 1635-1637. [Extract] [Full Text] [PDF]  

Jerry A. Katzmann

Serum Free Light Chain Specificity and Sensitivity: A Reality Check
Clin Chem 2006 52: 1638-1639. [Extract] [Full Text] [PDF]  

Michael Stowasser and Richard D. Gordon

Aldosterone Assays: An Urgent Need for Improvement
Clin Chem 2006 52: 1640-1642. [Extract] [Full Text] [PDF]  

Evan A. Stein

Are Measurements of LDL Particles Ready for Prime Time?
Clin Chem 2006 52: 1643-1644. [Extract] [Full Text] [PDF]  

Minireview:

Andrew Zalewski, Jeanenne J. Nelson, Lisa Hegg, and Colin Macphee

Lp-PLA₂: A New Kid on the Block
Clin Chem 2006 52: 1645-1650. Published online July 27, 2006; 10.1373/clinchem.2006.070672 [Abstract] [Full Text] [PDF]  

Reviews:

Marta Sanchez-Carbayo

Antibody Arrays: Technical Considerations and Clinical Applications in Cancer
Clin Chem 2006 52: 1651-1659. Published online June 29, 2006; 10.1373/clinchem.2005.059592 [Abstract] [Full Text] [PDF]  

Emma Parkinson-Lawrence, Maria Fuller, John J. Hopwood, Peter J. Meikle, and Doug A. Brooks

Immunochemistry of Lysosomal Storage Disorders
Clin Chem 2006 52: 1660-1668. Published online July 13, 2006; 10.1373/clinchem.2005.064915 [Abstract] [Full Text] [PDF]  

Overview:

Peter E. Barker, Paul D. Wagner, Stephen E. Stein, David M. Bunk, Sudhir Srivastava, and Gilbert S. Omenn

Standards for Plasma and Serum Proteomics in Early Cancer Detection: A Needs Assessment Report from the National Institute of Standards and Technology-National Cancer Institute Standards, Methods, Assays, Reagents and Technologies Workshop, August 18–19, 2005
Clin Chem 2006 52: 1669-1674. Published online July 13, 2006; 10.1373/clinchem.2006.067249 [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Michael R. James, Troy Dumeni, Mitchell S. Stark, David L. Duffy, Grant W. Montgomery, Nicholas G. Martin, and Nicholas K. Hayward

Rapid Screening of 4000 Individuals for Germ-line Variations in the BRAF Gene
Clin Chem 2006 52: 1675-1678. Published online July 27, 2006; 10.1373/clinchem.2006.070169 [Abstract] [Full Text] [PDF]  

Evidence-Based Laboratory Medicine and Test Utilization:

Giorgio Mello, Parretti Elena, Agostino Ognibene, Riccardo Cioni, Filippo Tondi, Paola Pezzati, Monica Pratesi, Gianfranco Scarselli, and Gianni Messeri

Lack of Concordance between the 75-g and 100-g Glucose Load Tests for the Diagnosis of Gestational Diabetes Mellitus
Clin Chem 2006 52: 1679-1684. Published online July 27, 2006; 10.1373/clinchem.2005.058040 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Robert H. Christenson, Show Hong Duh, Fred S. Apple, Geza S. Bodor, David M. Bunk, Mauro Panteghini, Michael J. Welch, Alan H.B. Wu, Stephen E. Kahn for the American Association for Clinical Chemistry Cardiac Troponin I Standardization Committee

Toward Standardization of Cardiac Troponin I Measurements Part II: Assessing Commutability of Candidate Reference Materials and Harmonization of Cardiac Troponin I Assays
Clin Chem 2006 52: 1685-1692. Published online July 20, 2006; 10.1373/clinchem.2006.068437 [Abstract] [Full Text] [PDF] 068437.Supplemental Data: Example calculation  

Cancer Diagnostics:

Paul N. Span, Vivianne C.G. Tjan-Heijnen, Joop J.T.M. Heuvel, Jacques B. de Kok, John A. Foekens, and Fred C.G.J. Sweep

Do the Survivin (BIRC5) Splice Variants Modulate or Add to the Prognostic Value of Total Survivin in Breast Cancer?
Clin Chem 2006 52: 1693-1700. Published online July 27, 2006; 10.1373/clinchem.2006.071613 [Abstract] [Full Text] [PDF]  

Nora Berois, Etienne Blanc, Hugues Ripoche, Xénia Mergui, Felipe Trajtenberg, Sabrina Cantais, Michel Barrois, Philippe Dessen, Bertil Kågedal, Jean Bénard, Eduardo Osinaga, and Gilda Raguénez

ppGalNAc-T13: A New Molecular Marker of Bone Marrow Involvement in Neuroblastoma
Clin Chem 2006 52: 1701-1712. Published online July 27, 2006; 10.1373/clinchem.2006.067975 [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Omar F. Laterza, Vijay R. Modur, Dan L. Crimmins, Jitka V. Olander, Yvonne Landt, Jin-Moo Lee, and Jack H. Ladenson

Identification of Novel Brain Biomarkers
Clin Chem 2006 52: 1713-1721. Published online July 20, 2006; 10.1373/clinchem.2006.070912 [Abstract] [Full Text] [PDF]  

Wayne Ensign, Nicole Hill, and Christopher B. Heward

Disparate LDL Phenotypic Classification among 4 Different Methods Assessing LDL Particle Characteristics
Clin Chem 2006 52: 1722-1727. Published online June 1, 2006; 10.1373/clinchem.2005.059949 [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Stephane O. Pirnay, Tsadik T. Abraham, and Marilyn A. Huestis

Sensitive Gas Chromatography-Mass Spectrometry Method for Simultaneous Measurement of MDEA, MDMA, and Metabolites HMA, MDA, and HMMA in Human Urine
Clin Chem 2006 52: 1728-1734. Published online July 20, 2006; 10.1373/clinchem.2006.069054 [Abstract] [Full Text] [PDF] 069054.Supplemental data  

François-Ludovic Sauvage, Franck Saint-marcoux, Bénédicte Duretz, Didier Deporte, Gérard Lachatre, and Pierre Marquet

Screening of Drugs and Toxic Compounds with Liquid Chromatography-Linear Ion Trap Tandem Mass Spectrometry
Clin Chem 2006 52: 1735-1742. Published online July 20, 2006; 10.1373/clinchem.2006.067116 [Abstract] [Full Text] [PDF] 067116.Supplemental Data  

Hematology:

Peter G. Hill, Julia M. Forsyth, Baldeep Rai, and Stewart Mayne

Serum Free Light Chains: An Alternative to the Urine Bence Jones Proteins Screening Test for Monoclonal Gammopathies
Clin Chem 2006 52: 1743-1748. Published online July 20, 2006; 10.1373/clinchem.2006.069104 [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Caroline Schirpenbach, Lysann Seiler, Christiane Maser-Gluth, Felix Beuschlein, Martin Reincke, and Martin Bidlingmaier

Automated Chemiluminescence-Immunoassay for Aldosterone during Dynamic Testing: Comparison to Radioimmunoassays with and without Extraction Steps
Clin Chem 2006 52: 1749-1755. Published online July 20, 2006; 10.1373/clinchem.2006.068502 [Abstract] [Full Text] [PDF]  

Eszter Szantai, Zsolt Ronai, Maria Sasvari-Szekely, Günther Bonn, and András Guttman

Multicapillary Electrophoresis Analysis of Single-Nucleotide Sequence Variations in the Deoxycytidine Kinase Gene
Clin Chem 2006 52: 1756-1762. Published online July 20, 2006; 10.1373/clinchem.2006.071159 [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Jirí Bronsky, Michal Karpísek, Eva Bronská, Marta Pechová, Barbora Jancíková, Hana Kotolová, David Stejskal, Richard Prusa, and Jirí Nevoral

Adiponectin, Adipocyte Fatty Acid Binding Protein, and Epidermal Fatty Acid Binding Protein: Proteins Newly Identified in Human Breast Milk
Clin Chem 2006 52: 1763-1770. Published online July 27, 2006; 10.1373/clinchem.2005.063032 [Abstract] [Full Text] [PDF]  

Tom Cantor, Zan Yang, Nicolae Caraiani, and Ekambaram Ilamathi

Lack of Comparability of Intact Parathyroid Hormone Measurements among Commercial Assays for End-Stage Renal Disease Patients: Implication for Treatment Decisions
Clin Chem 2006 52: 1771-1776. Published online July 20, 2006; 10.1373/clinchem.2006.071589 [Abstract] [Full Text] [PDF]  

Willem de Ronde, Yvonne T. van der Schouw, Huibert A.P. Pols, Louis J.G. Gooren, Majon Muller, Diederick E. Grobbee, and Frank H. de Jong

Calculation of Bioavailable and Free Testosterone in Men: A Comparison of 5 Published Algorithms
Clin Chem 2006 52: 1777-1784. Published online June 22, 2006; 10.1373/clinchem.2005.063354 [Abstract] [Full Text] [PDF]  

Clinical Immunology:

Erna Van Hoeyveld, Lieven Dupont, and Xavier Bossuyt

Quantification of IgG Antibodies to Aspergillus fumigatus and Pigeon Antigens by ImmunoCAP Technology: An Alternative to the Precipitation Technique?
Clin Chem 2006 52: 1785-1793. Published online July 20, 2006; 10.1373/clinchem.2006.067546 [Abstract] [Full Text] [PDF]  

Point-of-Care Testing:

Saara Wittfooth, Qiu-Ping Qin, Juha Lund, Ilkka Tierala, Kari Pulkki, Harri Takalo, and Kim Pettersson

Immunofluorometric Point-of-Care Assays for the Detection of Acute Coronary Syndrome-Related Noncomplexed Pregnancy-Associated Plasma Protein A
Clin Chem 2006 52: 1794-1801. Published online June 29, 2006; 10.1373/clinchem.2006.070607 [Abstract] [Full Text] [PDF] 070607.Supplemental data  

Nadia Aspromonte, Vincenzo Ceci, Antonella Chiera, Claudio Coletta, Alessandra D’Eri, Mauro Feola, Prospero Giovinazzo, Loredano Milani, Federica Noventa, Angela Beatrice Scardovi, Augusto Sestili, and Roberto Valle

Rapid Brain Natriuretic Peptide Test and Doppler Echocardiography for Early Diagnosis of Mild Heart Failure
Clin Chem 2006 52: 1802-1808. Published online July 27, 2006; 10.1373/clinchem.2005.064386 [Abstract] [Full Text] [PDF]  

Case Conference:

Kimberley G. Crone, Michele B. Muraski, Joy D. Skeel, Latisha Love-Gregory, Jack H. Ladenson, and Ann M. Gronowski

Between a Rock and a Hard Place: Disclosing Medical Errors
Clin Chem 2006 52: 1809-1814. Published online July 20, 2006; 10.1373/clinchem.2006.072678 [Abstract] [Full Text] [PDF]  

Technical Briefs:

Axel M. Gressner, Eray Yagmur, Birgit Lahme, Olav Gressner, and Sven Stanzel

Connective Tissue Growth Factor in Serum as a New Candidate Test for Assessment of Hepatic Fibrosis
Clin Chem 2006 52: 1815-1817. Published online July 20, 2006; 10.1373/clinchem.2006.070466 [Abstract] [Full Text] [PDF]  

Katleen Van Uytfanghe, Dietmar Stöckl, H Alec Ross, and Linda M. Thienpont

Use of Frozen Sera for FT4 Standardization: Investigation by Equilibrium Dialysis Combined with Isotope Dilution-Mass Spectrometry and Immunoassay
Clin Chem 2006 52: 1817-1821. Published online July 13, 2006; 10.1373/clinchem.2006.070425 [Abstract] [Full Text] [PDF] 070425.Supplemental Data  

Ioannis G. Fatouros, Aspasia Destouni, Konstantinos Margonis, Athanasios Z. Jamurtas, Christina Vrettou, Dimitrios Kouretas, George Mastorakos, Asimina Mitrakou, Kiriakos Taxildaris, Emmanouel Kanavakis, and Ioannis Papassotiriou

Cell-Free Plasma DNA as a Novel Marker of Aseptic Inflammation Severity Related to Exercise Overtraining
Clin Chem 2006 52: 1820-1824. Published online July 13, 2006; 10.1373/clinchem.2006.070417 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Duk-Hee Lee and David R. Jacobs, Jr

Association between Serum Concentrations of Persistent Organic Pollutants and Glutamyltransferase: Results from the National Health and Examination Survey 1999–2002
Clin Chem 2006 52: 1825-1827. [Extract] [Full Text] [PDF]  

Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, and Gian Cesare Guidi

Reliability of the Thrombin-Generation Assay in Frozen-Thawed Platelet-Rich Plasma
Clin Chem 2006 52: 1827-1828. [Extract] [Full Text] [PDF]  

Kunihiro Iwahara, Chizuko Tanabe, and Masato Maekawa

Dilution Test for Differentiating Falsely High Serum Free Triiodothyronine Concentrations
Clin Chem 2006 52: 1828-1829. [Extract] [Full Text] [PDF]  

Karsten Müssig, Albrecht Pfäfflin, Hans-Ulrich Häring, and Erwin D. Schleicher

Dipyrone (Metamizole) Metabolites Interfere with HPLC Analysis of Plasma Catecholamines but Not with the Determination of Urinary Catecholamines
Clin Chem 2006 52: 1829-1831. [Extract] [Full Text] [PDF]  

Book, Software, and Web Site Reviews:

Linda M. Thienpont

Hormone Assays in Biological Fluids. Michael J. Wheeler and J.S. Morley Hutchinson, eds. Totowa, NJ: Human Press, 2006, 258 pp., $99.50, hardcover.
Clin Chem 2006 52: 1832. [Extract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.