Editorials:

Christina Dahl and Per Guldberg

High-Resolution Melting for Accurate Assessment of DNA Methylation
Clin Chem 2007 53: 1877-1878. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Robert E. Pyatt, David C. Mihal, and Thomas W. Prior

Assessment of Liquid Microbead Arrays for the Screening of Newborns for Spinal Muscular Atrophy
Clin Chem 2007 53: 1879-1885. Published online September 21, 2007; 10.1373/clinchem.2007.092312 [Abstract] [Full Text] [PDF] 092312.Supplemental Data  

Cristina Vassalle, Maria Grazia Andreassi, Concetta Prontera, Marianna Fontana, Luc Zyw, Claudio Passino, and Michele Emdin

Influence of ScaI and Natriuretic Peptide (NP) Clearance Receptor Polymorphisms of the NP System on NP Concentration in Chronic Heart Failure
Clin Chem 2007 53: 1886-1890. Published online September 21, 2007; 10.1373/clinchem.2007.088302 [Abstract] [Full Text] [PDF] 088302.Supplemental Data  

Jesse Montgomery, Carl T. Wittwer, Jana O. Kent, and Luming Zhou

Scanning the Cystic Fibrosis Transmembrane Conductance Regulator Gene Using High-Resolution DNA Melting Analysis
Clin Chem 2007 53: 1891-1898. Published online September 21, 2007; 10.1373/clinchem.2007.092361 [Abstract] [Full Text] [PDF] 092361.Supplemental Data  

Marit Kramski, Helga Meisel, Boris Klempa, Detlev H. Krüger, Georg Pauli, and Andreas Nitsche

Detection and Typing of Human Pathogenic Hantaviruses by Real-Time Reverse Transcription-PCR and Pyrosequencing
Clin Chem 2007 53: 1899-1905. Published online August 23, 2007; 10.1373/clinchem.2007.093245 [Abstract] [Full Text] [PDF] 093245.Supplemental Data  

Yu K. Tong, Rossa W.K. Chiu, Tak Y. Leung, Chunming Ding, Tze K. Lau, Tse N. Leung, and Y.M. Dennis Lo

Detection of Restriction Enzyme–Digested Target DNA by PCR Amplification Using a Stem-Loop Primer: Application to the Detection of Hypomethylated Fetal DNA in Maternal Plasma
Clin Chem 2007 53: 1906-1914. Published online September 27, 2007; 10.1373/clinchem.2007.092619 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Nitin Seam, Denise A. Gonzales, Steven J. Kern, Glen L. Hortin, Gerard T. Hoehn, and Anthony F. Suffredini

Quality Control of Serum Albumin Depletion for Proteomic Analysis
Clin Chem 2007 53: 1915-1920. Published online September 21, 2007; 10.1373/clinchem.2007.091736 [Abstract] [Full Text] [PDF]  

Mads Nybo, Marianne Benn, Rasmus Mogelvang, Jan Skov Jensen, Peter Schnohr, Jens F. Rehfeld, and Jens Peter Goetze

Impact of Hemoglobin on Plasma Pro-B-Type Natriuretic Peptide Concentrations in the General Population
Clin Chem 2007 53: 1921-1927. Published online September 14, 2007; 10.1373/clinchem.2007.089391 [Abstract] [Full Text] [PDF]  

Endocrinology and Metabolism:

Morten Schou, Finn Gustafsson, Caroline N. Kistorp, Pernille Corell, Andreas Kjaer, and Per R. Hildebrandt

Effects of Body Mass Index and Age on N-Terminal Pro–Brain Natriuretic Peptide Are Associated with Glomerular Filtration Rate in Chronic Heart Failure Patients
Clin Chem 2007 53: 1928-1935. Published online September 14, 2007; 10.1373/clinchem.2006.084426 [Abstract] [Full Text] [PDF] 084426.Supplemental Data  

Sweta Rani, Martin Clynes, and Lorraine O’Driscoll

Detection of Amplifiable mRNA Extracellular to Insulin-Producing Cells: Potential for Predicting Beta Cell Mass and Function
Clin Chem 2007 53: 1936-1944. Published online August 23, 2007; 10.1373/clinchem.2007.087973 [Abstract] [Full Text] [PDF] 087973.Supplemental Data  

General Clinical Chemistry:

Mitchell G. Scott, Susan Morin, Karl G. Hock, Melles Seyoum, and Jack H. Ladenson

Establishing a Simple and Sustainable Quality Assurance Program and Clinical Chemistry Services in Eritrea
Clin Chem 2007 53: 1945-1953. [Abstract] [Full Text] [PDF] 093039.Supplemental Data  

Other Areas of Clinical Chemistry:

David W. Windus, Jack H. Ladenson, Cindy K. Merrins, Melles Seyoum, Debra Windus, Susan Morin, Beyene Tewelde, Curtis A. Parvin, Mitchell G. Scott, and Jason Goldfeder

Impact of a Multidisciplinary Intervention for Diabetes in Eritrea
Clin Chem 2007 53: 1954-1959. [Abstract] [Full Text] [PDF]  

Technical Briefs:

Helen E. White, Victoria J. Hall, and Nicholas C.P. Cross

Methylation-Sensitive High-Resolution Melting-Curve Analysis of the SNRPN Gene as a Diagnostic Screen for Prader-Willi and Angelman Syndromes
Clin Chem 2007 53: 1960-1962. Published online September 21, 2007; 10.1373/clinchem.2007.093351 [Abstract] [Full Text] [PDF]  

Guorong Chen, Lori Kobayashi, and Irina Nazarenko

Effect of Sample Aliquot Size on the Limit of Detection and Reproducibility of Clinical Assays
Clin Chem 2007 53: 1962-1965. Published online August 30, 2007; 10.1373/clinchem.2007.089854 [Abstract] [Full Text] [PDF] 089854.Supplemental Data  

Christine A. White, Ayub Akbari, Steve Doucette, Dean Fergusson, Naser Hussain, Laurent Dinh, Guido Filler, Nathalie Lepage, and Greg A. Knoll

A Novel Equation to Estimate Glomerular Filtration Rate Using Beta-Trace Protein
Clin Chem 2007 53: 1965-1968. Published online August 30, 2007; 10.1373/clinchem.2007.090126 [Abstract] [Full Text] [PDF] 090126.Supplemental data  

Giulio Mengozzi, Denis Rossato, Chiara Bertello, Corrado Garrone, Alberto Milan, Roberto Pagni, Franco Veglio, and Paolo Mulatero

Rapid Cortisol Assay during Adrenal Vein Sampling in Patients with Primary Aldosteronism
Clin Chem 2007 53: 1968-1971. Published online September 27, 2007; 10.1373/clinchem.2007.092080 [Abstract] [Full Text] [PDF]  

Masako Fujita, Eleanor Brindle, Jane Shofer, Philip Ndemwa, Yeri Kombe, Bettina Shell-Duncan, and Kathleen A. O’Connor

Retinol-Binding Protein Stability in Dried Blood Spots
Clin Chem 2007 53: 1972-1975. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Albrecht Pfäfflin, Erwin Schleicher, and Karsten Müssig

3-O-Methyldopamine (3-O-Methoxytyramine) Interferes with the Internal Standard 3,4-Dihydroxybenzylamine in a Plasma Catecholamine HPLC Method
Clin Chem 2007 53: 1976-1977. [Extract] [Full Text] [PDF]  

Isa Cavaco, Sara Asimus, Myriam Peyrard-Janvid, Pedro E. Ferreira, M. Isabel Veiga, Trinh Ngoc Hai, Vera Ribeiro, Michael Ashton, and J. Pedro Gil

The Vietnamese Khin Population Harbors Particular N-Acetyltransferase 2 Allele Frequencies
Clin Chem 2007 53: 1977-1979. [Extract] [Full Text] [PDF]  

Phillip R. Bach, Brian W. Davis, David Loughmiller, Janet Oertli, and Jacquie Taylor

C-Reactive Protein (CRP) in Neonates: Comparing VITROS Slide and High-Sensitivity CRP Methods
Clin Chem 2007 53: 1979-1981. [Extract] [Full Text] [PDF]  

Ferdinando Mannello, Gaetana A. Tonti, Jose E. Tanus-Santos, and Raquel F. Gerlach

Silicate Increases the Release of MMP-9 Forms in Peripheral Blood: Why Gelatin Zymography Differs Significantly in Citrate Plasma and Serum Obtained with or without Clot Activators
Clin Chem 2007 53: 1981-1982. [Extract] [Full Text] [PDF]  

Nynke Smidt, John Overbeke, Henrica de Vet, and Patrick Bossuyt

Endorsement of the STARD Statement by Biomedical Journals: Survey of Instructions for Authors
Clin Chem 2007 53: 1983-1985. [Extract] [Full Text] [PDF]  

Sandrine Daval, Arlette Tridon, Nicole Mazeron, Jean-Michel Ristori, and Bertrand Evrard

Risk of Antigen Excess in Serum Free Light Chain Measurements
Clin Chem 2007 53: 1985-1986. [Extract] [Full Text] [PDF]  

Tuija Männistö, Heljä-Marja Surcel, Aini Bloigu, Aimo Ruokonen, Anna-Liisa Hartikainen, Marjo-Riitta Järvelin, Anneli Pouta, Marja Vääräsmäki, and Eila Suvanto-Luukkonen

The Effect of Freezing, Thawing, and Short- and Long-Term Storage on Serum Thyrotropin, Thyroid Hormones, and Thyroid Autoantibodies: Implications for Analyzing Samples Stored in Serum Banks
Clin Chem 2007 53: 1986-1987. [Extract] [Full Text] [PDF]  

Vincent Rigalleau, Marie-Christine Beauvieux, Catherine Lasseur, Philippe Chauveau, Christelle Raffaitin, Caroline Perlemoine, Nicole Barthe, Christian Combe, and Henri Gin

The Combination of Cystatin C and Serum Creatinine Improves the Monitoring of Kidney Function in Patients with Diabetes and Chronic Kidney Disease
Clin Chem 2007 53: 1988-1989. [Extract] [Full Text] [PDF]  

Oak Ridge Conference:

John Todd, Bob Freese, Ann Lu, Douglas Held, Jennifer Morey, Richard Livingston, and Philippe Goix

Ultrasensitive Flow-based Immunoassays Using Single-Molecule Counting
Clin Chem 2007 53: 1990-1995. Published online September 21, 2007; 10.1373/clinchem.2007.091181 [Abstract] [Full Text] [PDF]  

Gautam V. Soni and Amit Meller

Progress toward Ultrafast DNA Sequencing Using Solid-State Nanopores
Clin Chem 2007 53: 1996-2001. Published online September 21, 2007; 10.1373/clinchem.2007.091231 [Abstract] [Full Text] [PDF]  

Kewal K. Jain

Applications of Nanobiotechnology in Clinical Diagnostics
Clin Chem 2007 53: 2002-2009. Published online September 21, 2007; 10.1373/clinchem.2007.090795 [Abstract] [Full Text] [PDF]  

Abstracts of Oak Ridge Posters:

Haoqun Qiu, Evan P. Ferrell, Niamh Nolan, Bruce H. Phelps, Raymond Tabibiazar, Duncan H. Whitney, and Eric A. Nalefski

Fluorescence Single-Molecule Counting Assays for High-Sensitivity Detection of Cytokines and Chemokines
Clin Chem 2007 53: 2010-2012. [Extract] [Full Text] [PDF] 091306.Supplemental Data  

Nichola C. Garbett, James J. Miller, A. Bennett Jenson, Donald M. Miller, and Jonathan B. Chaires

Interrogation of the Plasma Proteome with Differential Scanning Calorimetry
Clin Chem 2007 53: 2012-2014. [Extract] [Full Text] [PDF] 091165.Supplemental Data  

Piia von Lode, Anniina Syrjälä, Virve Hagren, Hannu Kojola, Tero Soukka, Timo Lövgren, and Jussi Nurmi

Fully Automated, Homogeneous Nucleic Acid Detection Technology Based on Dry-Reagent Assay Chemistry and Time-Resolved Fluorometry
Clin Chem 2007 53: 2014-2017. [Extract] [Full Text] [PDF]  

Eric Tan, Barbara Erwin, Shale Dames, Karl Voelkerding, and Angelika Niemz

Isothermal DNA Amplification with Gold Nanosphere-Based Visual Colorimetric Readout for Herpes Simplex Virus Detection
Clin Chem 2007 53: 2017-2020. [Extract] [Full Text] [PDF] 091116.Supplemental Data  

Karel Boissinot, Ann Huletsky, Régis Peytavi, Sophie Turcotte, Véronique Veillette, Maurice Boissinot, François J. Picard, Eric A. Martel, and Michel G. Bergeron

Rapid Exonuclease Digestion of PCR-Amplified Targets for Improved Microarray Hybridization
Clin Chem 2007 53: 2020-2023. [Extract] [Full Text] [PDF] 091157.Supplemental Data  

Aditya S. Bedekar, Yi Wang, Sachin S. Siddhaye, Siva Krishnamoorthy, and Stephen F. Malin

Design Software for Application-Specific Microfluidic Devices
Clin Chem 2007 53: 2023-2026. [Extract] [Full Text] [PDF]  

Diana Cristina Rambaldi, Andrea Zattoni, Sonia Casolari, Pierluigi Reschiglian, Dierk Roessner, and Christoph Johann

An Analytical Method for Size and Shape Characterization of Blood Lipoproteins
Clin Chem 2007 53: 2026-2029. [Extract] [Full Text] [PDF]  

Chitta Ranjan Patra, Resham Bhattacharya, Sujata Patra, Sujit Basu, Priyabrata Mukherjee, and Debabrata Mukhopadhyay

Lanthanide Phosphate Nanorods as Inorganic Fluorescent Labels in Cell Biology Research
Clin Chem 2007 53: 2029-2031. [Extract] [Full Text] [PDF] 091207.Supplemental Data  

Nisar A. Shaikh, Jun Ge, Yi-Xue Zhao, Paul Walker, and Mike Drebot

Development of a Novel, Rapid, and Sensitive Immunochromatographic Strip Assay Specific for West Nile Virus (WNV) IgM and Testing of Its Diagnostic Accuracy in Patients Suspected of WNV Infection
Clin Chem 2007 53: 2031-2034. [Extract] [Full Text] [PDF]  

Sharon Banin, Stuart Wilson, and Christopher Stanley

The LiMA Technology: Measurement of ATP on a Nucleic Acid Testing Platform
Clin Chem 2007 53: 2034-2036. [Extract] [Full Text] [PDF]  

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