Editorials:

Anthony G.W. Norden, Pedro Rodriguez-Cutillas, and Robert J. Unwin

Clinical Urinary Peptidomics: Learning to Walk Before We Can Run
Clin Chem 2007 53: 375-376. [Extract] [Full Text] [PDF]  

Current Issues in Laboratory Medicine:

Rob N.M. Weijers and Dick J. Bekedam

Relationship between Gestational Diabetes Mellitus and Type 2 Diabetes: Evidence of Mitochondrial Dysfunction
Clin Chem 2007 53: 377-383. [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Kyriaki Glynou, Petros Kastanis, Sotiria Boukouvala, Vassilis Tsaoussis, Penelope C. Ioannou, Theodore K. Christopoulos, Joanne Traeger-Synodinos, and Emmanuel Kanavakis

High-Throughput Microtiter Well-Based Chemiluminometric Genotyping of 15 HBB Gene Mutations in a Dry-Reagent Format
Clin Chem 2007 53: 384-391. Published online January 26, 2007; 10.1373/clinchem.2006.077776 [Abstract] [Full Text] [PDF] 077776.Supplemental Data  

Dianna C. Martin, Brian L. Mark, Barbara L. Triggs-Raine, and Marvin R. Natowicz

Evaluation of the Risk for Tay-Sachs Disease in Individuals of French Canadian Ancestry Living in New England
Clin Chem 2007 53: 392-398. Published online January 26, 2007; 10.1373/clinchem.2006.082727 [Abstract] [Full Text] [PDF]  

Yuditiya Purwosunu, Akihiko Sekizawa, Keiko Koide, Antonio Farina, Noroyono Wibowo, Gulardi Hanifa Wiknjosastro, Shiho Okazaki, Hiroshi Chiba, and Takashi Okai

Cell-Free mRNA Concentrations of Plasminogen Activator Inhibitor-1 and Tissue-Type Plasminogen Activator Are Increased in the Plasma of Pregnant Women with Preeclampsia
Clin Chem 2007 53: 399-404. Published online January 18, 2007; 10.1373/clinchem.2006.081372 [Abstract] [Full Text] [PDF]  

Olav Lapaire, Diana W. Bianchi, Inga Peter, Barbara O’Brien, Helene Stroh, Janet M. Cowan, Umadevi Tantravahi, and Kirby L. Johnson

Cell-Free Fetal DNA in Amniotic Fluid: Unique Fragmentation Signatures in Euploid and Aneuploid Fetuses
Clin Chem 2007 53: 405-411. Published online January 26, 2007; 10.1373/clinchem.2006.076083 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Rahul Sakhuja, Sandy Green, Eveline M. Oestreicher, Patrick M. Sluss, Elizabeth Lee-Lewandrowski, Kent B. Lewandrowski, and James L. Januzzi, Jr.

Amino-Terminal Pro–Brain Natriuretic Peptide, Brain Natriuretic Peptide, and Troponin T for Prediction of Mortality in Acute Heart Failure
Clin Chem 2007 53: 412-420. Published online January 26, 2007; 10.1373/clinchem.2006.074047 [Abstract] [Full Text] [PDF] 074047.Supplemental Data  

Georg Martin Fiedler, Sven Baumann, Alexander Leichtle, Anke Oltmann, Julia Kase, Joachim Thiery, and Uta Ceglarek

Standardized Peptidome Profiling of Human Urine by Magnetic Bead Separation and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry
Clin Chem 2007 53: 421-428. Published online February 1, 2007; 10.1373/clinchem.2006.077834 [Abstract] [Full Text] [PDF] 077834.Supplemental Data  

Girish Sardana, John Marshall, and Eleftherios P. Diamandis

Discovery of Candidate Tumor Markers for Prostate Cancer via Proteomic Analysis of Cell Culture–Conditioned Medium
Clin Chem 2007 53: 429-437. Published online January 26, 2007; 10.1373/clinchem.2006.077370 [Abstract] [Full Text] [PDF] 077370.Supplemental Data  

Cancer Diagnostics:

Tine Børglum, Jens F. Rehfeld, Lars B. Drivsholm, and Linda Hilsted

Processing-Independent Quantitation of Chromogranin A in Plasma from Patients with Neuroendocrine Tumors and Small-Cell Lung Carcinomas
Clin Chem 2007 53: 438-446. Published online January 26, 2007; 10.1373/clinchem.2006.076158 [Abstract] [Full Text] [PDF] 076158.Supplemental Data  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Atsushi Hozawa, David R. Jacobs, Jr., Michael W. Steffes, Myron D. Gross, Lyn M. Steffen, and Duk-Hee Lee

Relationships of Circulating Carotenoid Concentrations with Several Markers of Inflammation, Oxidative Stress, and Endothelial Dysfunction: The Coronary Artery Risk Development in Young Adults (CARDIA)/Young Adult Longitudinal Trends in Antioxidants (YALTA) Study
Clin Chem 2007 53: 447-455. Published online January 18, 2007; 10.1373/clinchem.2006.074930 [Abstract] [Full Text] [PDF] 074930.Supplemental data  

Roya Kelishadi, Mohsen Sharifi, Alireza Khosravi, and Khosrow Adeli

Relationship Between C-Reactive Protein and Atherosclerotic Risk Factors and Oxidative Stress Markers Among Young Persons 10–18 Years Old
Clin Chem 2007 53: 456-464. Published online January 26, 2007; 10.1373/clinchem.2006.073668 [Abstract] [Full Text] [PDF]  

Drug Monitoring and Toxicology:

Jianming Guo, Feng Qian, Jianxin Li, Qiang Xu, and Ting Chen

Identification of a New Metabolite of Astilbin, 3'-O-Methylastilbin, and Its Immunosuppressive Activity against Contact Dermatitis
Clin Chem 2007 53: 465-471. Published online February 1, 2007; 10.1373/clinchem.2006.077297 [Abstract] [Full Text] [PDF] 077297.Supplemental Data  

Endocrinology and Metabolism:

Matti Ankelo, Annette Westerlund, Kaj Blomberg, Mikael Knip, Jorma Ilonen, and Ari E. Hinkkanen

Time-Resolved Immunofluorometric Dual-Label Assay for Simultaneous Detection of Autoantibodies to GAD65 and IA-2 in Children with Type 1 Diabetes
Clin Chem 2007 53: 472-479. Published online January 26, 2007; 10.1373/clinchem.2005.064568 [Abstract] [Full Text] [PDF]  

Laura Pucci, Stefano Triscornia, Daniela Lucchesi, Carmen Fotino, Giovanni Pellegrini, Ennia Pardini, Roberto Miccoli, Stefano Del Prato, and Giuseppe Penno

Cystatin C and Estimates of Renal Function: Searching for a Better Measure of Kidney Function in Diabetic Patients
Clin Chem 2007 53: 480-488. Published online January 26, 2007; 10.1373/clinchem.2006.076042 [Abstract] [Full Text] [PDF] 076042.Supplemental Data  

Manuel Haschke, Yan Ling Zhang, Christine Kahle, Jelena Klawitter, Magdalena Korecka, Leslie M. Shaw, and Uwe Christians

HPLC–Atmospheric Pressure Chemical Ionization MS/MS for Quantification of 15-F_2t-Isoprostane in Human Urine and Plasma
Clin Chem 2007 53: 489-497. Published online January 26, 2007; 10.1373/clinchem.2006.078972 [Abstract] [Full Text] [PDF] 078972.Supplemental Data  

Evidence-Based Laboratory Medicine and Test Utilization:

Dries Coenen, Patrick Verschueren, René Westhovens, and Xavier Bossuyt

Technical and Diagnostic Performance of 6 Assays for the Measurement of Citrullinated Protein/Peptide Antibodies in the Diagnosis of Rheumatoid Arthritis
Clin Chem 2007 53: 498-504. Published online January 26, 2007; 10.1373/clinchem.2006.078063 [Abstract] [Full Text] [PDF] 078063.Supplemental Data  

Clinical Immunology:

Axel Jeurissen, Leen Moens, Marc Raes, Greet Wuyts, Luc Willebrords, Kate Sauer, Marijke Proesmans, Jan L. Ceuppens, Kris De Boeck, and Xavier Bossuyt

Laboratory Diagnosis of Specific Antibody Deficiency to Pneumococcal Capsular Polysaccharide Antigens
Clin Chem 2007 53: 505-510. Published online January 26, 2007; 10.1373/clinchem.2006.080051 [Abstract] [Full Text] [PDF] 080051.Supplemental Data  

Nutrition:

Jason H.Y. Wu, Natalie C. Ward, Adeline P. Indrawan, Coral-Ann Almeida, Jonathan M. Hodgson, Julie M. Proudfoot, Ian B. Puddey, and Kevin D. Croft

Effects of -Tocopherol and Mixed Tocopherol Supplementation on Markers of Oxidative Stress and Inflammation in Type 2 Diabetes
Clin Chem 2007 53: 511-519. Published online February 1, 2007; 10.1373/clinchem.2006.076992 [Abstract] [Full Text] [PDF]  

Technical Briefs:

Pasquale Florio, Stefano Luisi, Bashir Moataza, Michela Torricelli, Iskander Iman, Mufeed Hala, Aboulgar Hanna, Felice Petraglia, and Diego Gazzolo

High Urinary Concentrations of Activin A in Asphyxiated Full-Term Newborns with Moderate or Severe Hypoxic Ischemic Encephalopathy
Clin Chem 2007 53: 520-522. Published online January 26, 2007; 10.1373/clinchem.2005.062604 [Abstract] [Full Text] [PDF] 062604.Supplemental Data  

Steven Se Fum Wong, Jeffrey J. Kuei, Naina Prasad, Etsemaye Agonafer, Gustavo A. Mendoza, Trevor J. Pemberton, and Pragna I. Patel

A Simple Method for DNA Isolation from Clotted Blood Extricated Rapidly from Serum Separator Tubes
Clin Chem 2007 53: 522-524. Published online January 18, 2007; 10.1373/clinchem.2006.078212 [Abstract] [Full Text] [PDF]  

Uma Singh, James Otvos, Amitava Dasgupta, James A. de Lemos, Sridevi Devaraj, and Ishwarlal Jialal

High-Dose -Tocopherol Therapy Does Not Affect HDL Subfractions in Patients with Coronary Artery Disease on Statin Therapy
Clin Chem 2007 53: 525-528. Published online January 18, 2007; 10.1373/clinchem.2006.078865 [Abstract] [Full Text] [PDF] 078865.Supplemental Data  

André B.P. van Kuilenburg, Henk van Lenthe, Lida Zoetekouw, and Willem Kulik

HPLC-Electrospray Tandem Mass Spectrometry for Rapid Determination of Dihydropyrimidine Dehydrogenase Activity
Clin Chem 2007 53: 528-530. Published online February 1, 2007; 10.1373/clinchem.2006.074096 [Abstract] [Full Text] [PDF] 074096.Supplemental Data  

Vilma Mantovani, Paolo Garagnani, Paola Selva, Cesare Rossi, Simona Ferrari, Marinella Cenci, Nilla Calza, Vincenzo Cerreta, Donata Luiselli, and Giovanni Romeo

Simple Method for Haplotyping the Poly(TG) Repeat in Individuals Carrying the IVS8 5T Allele in the CFTR Gene
Clin Chem 2007 53: 531-533. Published online January 18, 2007; 10.1373/clinchem.2006.074807 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Jasper A. Remijn, Johan R. Beukhof, and Lambert D. Dikkeschei

Large Fluctuations in Parathyroid Hormone Concentrations After Autotransplantation of Parathyroid Tissue in the Forearm
Clin Chem 2007 53: 534-535. [Extract] [Full Text] [PDF]  

Alessandra Barassi, Wanda Porreca, Loredana De Pasquale, Amelia Bastagli, and Gian Vico Melzi d’Eril

Use of Intraoperative Samples to Optimize Efficacy of Central Laboratory Parathyroid Hormone Analyses
Clin Chem 2007 53: 535-536. [Extract] [Full Text] [PDF]  

Dirk Vlasselaers, Lukas Schaupp, Ingeborg van den Heuvel, Julia Mader, Manfred Bodenlenz, Maria Suppan, Pieter Wouters, Martin Ellmerer, and Greet Van den Berghe

Monitoring Blood Glucose with Microdialysis of Interstitial Fluid in Critically Ill Children
Clin Chem 2007 53: 536-537. [Extract] [Full Text] [PDF]  

Catherine Alix-Panabières, Jean-Pierre Vendrell, Olivier Pellé, Xavier Rebillard, Sabine Riethdorf, Volkmar Müller, Michel Fabbro, and Klaus Pantel

Detection and Characterization of Putative Metastatic Precursor Cells in Cancer Patients
Clin Chem 2007 53: 537-539. [Extract] [Full Text] [PDF]  

Michael M. Hoffmann, Peter Bugert, Ursula Seelhorst, Britta Wellnitz, Bernhard R. Winkelmann, Bernhard O. Boehm, and Winfried März

The –50G>T Polymorphism in the Promoter of the CYP2J2 Gene in Coronary Heart Disease: The Ludwigshafen Risk and Cardiovascular Health Study
Clin Chem 2007 53: 539-540. [Extract] [Full Text] [PDF]  

Ravinder Singh, Frank W. Crow, Nikolina Babic, Ward H. Lutz, John C. Lieske, Timothy S. Larson, and Rajiv Kumar

A Liquid Chromatography-Mass Spectrometry Method for the Quantification of Urinary Albumin using a Novel ¹⁵N-Isotopically Labeled Albumin Internal Standard
Clin Chem 2007 53: 540-542. [Extract] [Full Text] [PDF] 078832.Supplemental Data  

Article:

Meeting Notice
Clin Chem 2007 53: 542. [Extract] [Full Text] [PDF]  

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