Editorials:

Ravinder J. Singh and Graeme Eisenhofer

High-Throughput, Automated, and Accurate Biochemical Screening for Pheochromocytoma: Are We There Yet?
Clin Chem 2007 53: 1565-1567. [Extract] [Full Text] [PDF]  

Harmut H.-J. Schmidt

Introducing Single-Nucleotide Polymorphism Markers in the Diagnosis of Wilson Disease
Clin Chem 2007 53: 1568-1569. [Extract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Nicholas J. Parham, François J. Picard, Régis Peytavi, Martin Gagnon, Grégoire Seyrig, Pier-Ann Gagné, Maurice Boissinot, and Michel G. Bergeron

Specific Magnetic Bead–Based Capture of Genomic DNA from Clinical Samples: Application to the Detection of Group B Streptococci in Vaginal/Anal Swabs
Clin Chem 2007 53: 1570-1576. Published online July 27, 2007; 10.1373/clinchem.2007.091389 [Abstract] [Full Text] [PDF]  

Silvia Parajes, Celsa Quinterio, Fernando Domínguez, and Lourdes Loidi

A Simple and Robust Quantitative PCR Assay to Determine CYP21A2 Gene Dose in the Diagnosis of 21-Hydroxylase Deficiency
Clin Chem 2007 53: 1577-1584. Published online July 18, 2007; 10.1373/clinchem.2007.087361 [Abstract] [Full Text] [PDF] 087361.Supplemental data  

Reza Meshkani, Mohammad Taghikhani, Hussam Al-Kateb, Bagher Larijani, Shohreh Khatami, Gus Konstantinos Sidiropoulos, Robert Alexander Hegele, and Khosrow Adeli

Polymorphisms within the Protein Tyrosine Phosphatase 1B (PTPN1) Gene Promoter: Functional Characterization and Association with Type 2 Diabetes and Related Metabolic Traits
Clin Chem 2007 53: 1585-1592. Published online July 18, 2007; 10.1373/clinchem.2007.088146 [Abstract] [Full Text] [PDF]  

Emily S. Winn-Deen, Bret Helton, Reuel Van Atta, Wendy Wong, Jeffrey Peralta, James Wang, Gregory J. Tsongalis, Dorothy Belloni, David Chan, James R. Eshleman, Christopher D. Gocke, Zsolt Jobbagy, Lan Beppu, and Jerald P. Radich

Development of an Integrated Assay for Detection of BCR-ABL RNA
Clin Chem 2007 53: 1593-1600. Published online July 27, 2007; 10.1373/clinchem.2007.085472 [Abstract] [Full Text] [PDF] 085472.Supplemental Data  

Arnab Gupta, Mahua Maulik, Poonam Nasipuri, Ishita Chattopadhyay, Shyamal K. Das, Prasanta K. Gangopadhyay, The Indian Genome Variation Consortium, and Kunal Ray

Molecular Diagnosis of Wilson Disease Using Prevalent Mutations and Informative Single-Nucleotide Polymorphism Markers
Clin Chem 2007 53: 1601-1608. Published online July 18, 2007; 10.1373/clinchem.2007.086066 [Abstract] [Full Text] [PDF] 086066.Supplemental Data  

Xiao-Yan Zhong, Ines von Mühlenen, Ying Li, Anjeung Kang, Anurag Kumar Gupta, Alan Tyndall, Wolfgang Holzgreve, Sinuhe Hahn, and Paul Hasler

Increased Concentrations of Antibody-Bound Circulatory Cell-Free DNA in Rheumatoid Arthritis
Clin Chem 2007 53: 1609-1614. [Abstract] [Full Text] [PDF]  

Evidence-Based Laboratory Medicine and Test Utilization:

Thierry Poynard, Philippe Halfon, Laurent Castera, Mona Munteanu, Françoise Imbert-Bismut, Vlad Ratziu, Yves Benhamou, Marc Bourlière, Victor de Ledinghen FibroPaca Group

Standardization of ROC Curve Areas for Diagnostic Evaluation of Liver Fibrosis Markers Based on Prevalences of Fibrosis Stages
Clin Chem 2007 53: 1615-1622. Published online July 18, 2007; 10.1373/clinchem.2007.085795 [Abstract] [Full Text] [PDF] 085795.Supplemental Data  

Alfredo Leaños-Miranda, Janeth Márquez-Acosta, Fernando Romero-Arauz, Guadalupe M. Cárdenas-Mondragón, Roxana Rivera-Leaños, Irma Isordia-Salas, and Alfredo Ulloa-Aguirre

Protein:Creatinine Ratio in Random Urine Samples Is a Reliable Marker of Increased 24-Hour Protein Excretion in Hospitalized Women with Hypertensive Disorders of Pregnancy
Clin Chem 2007 53: 1623-1628. Published online July 27, 2007; 10.1373/clinchem.2007.089334 [Abstract] [Full Text] [PDF]  

Hemostasis and Thrombosis:

Armando Tripodi

Laboratory Testing for Lupus Anticoagulants: A Review of Issues Affecting Results
Clin Chem 2007 53: 1629-1635. [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Hassan Dihazi, Gerhard A. Müller, Sandra Lindner, Markus Meyer, Abdul R. Asif, Michael Oellerich, and Frank Strutz

Characterization of Diabetic Nephropathy by Urinary Proteomic Analysis: Identification of a Processed Ubiquitin Form as a Differentially Excreted Protein in Diabetic Nephropathy Patients
Clin Chem 2007 53: 1636-1645. Published online July 18, 2007; 10.1373/clinchem.2007.088260 [Abstract] [Full Text] [PDF] 088260.Supplemental Data  

Cancer Diagnostics:

Hongzhi Zou, Jonathan Harrington, Rafaela L. Rego, and David A. Ahlquist

A Novel Method to Capture Methylated Human DNA from Stool: Implications for Colorectal Cancer Screening
Clin Chem 2007 53: 1646-1651. [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Robert B. Neuman, Heather L. Bloom, Irfan Shukrullah, Lyndsey A. Darrow, David Kleinbaum, Dean P. Jones, and Samuel C. Dudley, Jr

Oxidative Stress Markers Are Associated with Persistent Atrial Fibrillation
Clin Chem 2007 53: 1652-1657. Published online June 28, 2007; 10.1373/clinchem.2006.083923 [Abstract] [Full Text] [PDF] 083923.Supplemental Data  

Endocrinology and Metabolism:

Sonia L. La’ulu and William L. Roberts

Second-Trimester Reference Intervals for Thyroid Tests: The Role of Ethnicity
Clin Chem 2007 53: 1658-1664. [Abstract] [Full Text] [PDF] 089680.Supplemental Data  

Point-of-Care Testing:

Edited on behalf of the National Institute of Biomedical Imaging and Bioengineering/National Heart, Lung, and Blood Institute/National Science Foundation Workshop Faculty, Christopher P. Price, and Larry J. Kricka

Improving Healthcare Accessibility through Point-of-Care Technologies
Clin Chem 2007 53: 1665-1675. Published online July 27, 2007; 10.1373/clinchem.2006.084707 [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Christopher Bachran, Mark Sutherland, Diana Bachran, and Hendrik Fuchs

Quantification of Diphtheria Toxin–Mediated ADP-Ribosylation in a Solid-Phase Assay
Clin Chem 2007 53: 1676-1683. [Abstract] [Full Text] [PDF]  

Wilhelmina H.A. de Jong, Kendon S. Graham, Jan C. van der Molen, Thera P. Links, Michael R. Morris, H. Alec Ross, Elisabeth G.E. de Vries, and Ido P. Kema

Plasma Free Metanephrine Measurement Using Automated Online Solid-Phase Extraction HPLC–Tandem Mass Spectrometry
Clin Chem 2007 53: 1684-1693. [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Nathan G. Dodder, Susan S.-C. Tai, Lorna T. Sniegoski, Nien F. Zhang, and Michael J. Welch

Certification of Creatinine in a Human Serum Reference Material by GC-MS and LC-MS
Clin Chem 2007 53: 1694-1699. Published online July 27, 2007; 10.1373/clinchem.2007.090027 [Abstract] [Full Text] [PDF]  

Clinical Immunology:

Ming-Chu Chang, Yu-Ting Chang, Yu-Wen Tien, Po-Chin Liang, I-Shiow Jan, Shu-Chen Wei, and Jau-Min Wong

T-Cell Regulatory Gene CTLA-4 Polymorphism/Haplotype Association with Autoimmune Pancreatitis
Clin Chem 2007 53: 1700-1705. [Abstract] [Full Text] [PDF]  

Nutrition:

Mohammed K. Azharuddin, Denis St. J. O’Reilly, Andrew Gray, and Dinesh Talwar

HPLC Method for Plasma Vitamin K₁: Effect of Plasma Triglyceride and Acute-Phase Response on Circulating Concentrations
Clin Chem 2007 53: 1706-1713. [Abstract] [Full Text] [PDF] 086280.Supplemental Data  

Letters to the Editor:

John E.M. Midgley

Spurious Conclusions on Analog Free Thyroxine Assay Performance
Clin Chem 2007 53: 1714. [Extract] [Full Text] [PDF]  

Ankie Koeken, Ellen de Baar, Lianne Schrauwen, and Christa Cobbaert

Presence of the Hemochromatosis S65C Mutation Leads to Failure of Amplification in a Multiplex C282Y/H63D PCR
Clin Chem 2007 53: 1715. [Extract] [Full Text] [PDF]  

Jan S. Krouwer

A Recommended Improvement for Specifying and Estimating Serum Creatinine Performance
Clin Chem 2007 53: 1715-1716. [Extract] [Full Text] [PDF]  

W. Greg Miller, Gary L. Myers, and John H. Eckfeldt

The authors of the article cited above respond:
Clin Chem 2007 53: 1716-1717. [Extract] [Full Text] [PDF]  

Janne Unger, Gerlinde Filippi, and Wolfgang Patsch

Measurements of Free Hemoglobin and Hemolysis Index: EDTA- or Lithium-Heparinate Plasma?
Clin Chem 2007 53: 1717-1718. [Extract] [Full Text] [PDF]  

Stephen O. Brennan, Tim Chan, and Michael Beard

Hemoglobin Hagley Park: A Novel (82AlaThr) Substitution Identified in an Infant with Severe Hemolytic Anemia
Clin Chem 2007 53: 1718-1719. [Extract] [Full Text] [PDF]  

Christian Mueller

Comparison of the Diagnostic Accuracy of BNP and NT-proBNP in Acute and Chronic Heart Failure
Clin Chem 2007 53: 1719-1720. [Extract] [Full Text] [PDF]  

Aldo Clerico, Marianna Fontana, Luc Zyw, Claudio Passino, and Michele Emdin

The authors of the article cited above respond:
Clin Chem 2007 53: 1720-1721. [Extract] [Full Text] [PDF]  

Giuseppe Lippi, Gian Luca Salvagno, and Gian Cesare Guidi

Genetic Factors for Warfarin Dose Prediction
Clin Chem 2007 53: 1721-1722. [Extract] [Full Text] [PDF]  

Concetta Prontera, Antonio Fortunato, Simona Storti, Antonella Mercuri, Giovanni Longombardo, Gian Carlo Zucchelli, Michele Emdin, and Aldo Clerico

Evaluation of Analytical Performance of the Siemens ADVIA TnI Ultra Immunoassay
Clin Chem 2007 53: 1722-1723. [Extract] [Full Text] [PDF]  

Giovanni Baviera, Francesco Corrado, Corrado Dugo, Maria L. Cannata, Silvia Russo, and D’Anna Rosario

Midtrimester Amniotic Fluid Adiponectin in Normal Pregnancy
Clin Chem 2007 53: 1723-1724. [Extract] [Full Text] [PDF]  

Corrections:

Correction
Clin Chem 2007 53: 1724. [Extract] [Full Text] [PDF]  

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