Editorials:

Nader Rifai, Douglas G. Altman, and Patrick M. Bossuyt

Reporting Bias in Diagnostic and Prognostic Studies: Time for Action
Clin Chem 2008 54: 1101-1103. [Extract] [Full Text] [PDF]  

Stefan Holdenrieder, Frank T. Kolligs, and Petra Stieber

New Horizons for Diagnostic Applications of Circulating Nucleosomes in Blood?
Clin Chem 2008 54: 1104-1106. [Extract] [Full Text] [PDF]  

James L. Januzzi, Jr

Use of Biomarkers to Predict Cardiac Risk from Medications: Getting to the Heart of the Matter
Clin Chem 2008 54: 1107-1109. [Extract] [Full Text] [PDF]  

Perspectives:

Elizabeth A. Platz

Low Testosterone and Risk of Premature Death in Older Men: Analytical and Preanalytical Issues in Measuring Circulating Testosterone
Clin Chem 2008 54: 1110-1112. [Extract] [Full Text] [PDF]  

Peter O. Kwiterovich

Cut Points for Lipids and Lipoproteins in Children and Adolescents: Should They Be Reassessed?
Clin Chem 2008 54: 1113-1115. [Extract] [Full Text] [PDF]  

Review:

Struan F. A. Grant and Hakon Hakonarson

Microarray Technology and Applications in the Arena of Genome-Wide Association
Clin Chem 2008 54: 1116-1124. Published online May 22, 2008; 10.1373/clinchem.2008.105395 [Abstract] [Full Text] [PDF]  

Molecular Diagnostics and Genetics:

Ugur Deligezer, Ebru E. Akisik, Nilgün Erten, and Nejat Dalay

Sequence-Specific Histone Methylation Is Detectable on Circulating Nucleosomes in Plasma
Clin Chem 2008 54: 1125-1131. Published online May 16, 2008; 10.1373/clinchem.2007.101766 [Abstract] [Full Text] [PDF] Supplemental Data  

Ester Castellsagué, Sara González, Marga Nadal, Olga Campos, Elisabet Guinó, Miguel Urioste, Ignacio Blanco, Thierry Frebourg, and Gabriel Capellá

Detection of APC Gene Deletions Using Quantitative Multiplex PCR of Short Fluorescent Fragments
Clin Chem 2008 54: 1132-1140. Published online May 16, 2008; 10.1373/clinchem.2007.101006 [Abstract] [Full Text] [PDF] Supplemental Data  

Lee-Jun C. Wong, David Dimmock, Michael T. Geraghty, Richard Quan, Uta Lichter-Konecki, Jing Wang, Ellen K. Brundage, Fernando Scaglia, and A. Craig Chinault

Utility of Oligonucleotide Array–Based Comparative Genomic Hybridization for Detection of Target Gene Deletions
Clin Chem 2008 54: 1141-1148. Published online May 16, 2008; 10.1373/clinchem.2008.103721 [Abstract] [Full Text] [PDF]  

Proteomics and Protein Markers:

Kay Brune, Hugo A. Katus, Joachim Moecks, Eberhard Spanuth, Allan S. Jaffe, and Evangelos Giannitsis

N-Terminal Pro–B-Type Natriuretic Peptide Concentrations Predict the Risk of Cardiovascular Adverse Events from Antiinflammatory Drugs: A Pilot Trial
Clin Chem 2008 54: 1149-1157. Published online May 1, 2008; 10.1373/clinchem.2007.097428 [Abstract] [Full Text] [PDF] Supplemental Data  

John B. Whitfield, Veronica Dy, Pamela A.F. Madden, Andrew C. Heath, Nicholas G. Martin, and Grant W. Montgomery

Measuring Carbohydrate-Deficient Transferrin by Direct Immunoassay: Factors Affecting Diagnostic Sensitivity for Excessive Alcohol Intake
Clin Chem 2008 54: 1158-1165. Published online May 16, 2008; 10.1373/clinchem.2007.101733 [Abstract] [Full Text] [PDF] Supplemental Data  

Zuzana Kyselova, Yehia Mechref, Pilsoo Kang, John A. Goetz, Lacey E. Dobrolecki, George W. Sledge, Lauren Schnaper, Robert J. Hickey, Linda H. Malkas, and Milos V. Novotny

Breast Cancer Diagnosis and Prognosis through Quantitative Measurements of Serum Glycan Profiles
Clin Chem 2008 54: 1166-1175. Published online May 16, 2008; 10.1373/clinchem.2007.087148 [Abstract] [Full Text] [PDF] Supplemental Data  

Christina Kanaka-Gantenbein, Alexandra Margeli, Panagiota Pervanidou, Sophia Sakka, George Mastorakos, George P. Chrousos, and Ioannis Papassotiriou

Retinol-Binding Protein 4 and Lipocalin-2 in Childhood and Adolescent Obesity: When Children Are Not Just "Small Adults"
Clin Chem 2008 54: 1176-1182. Published online May 16, 2008; 10.1373/clinchem.2007.099002 [Abstract] [Full Text] [PDF]  

Lipids, Lipoproteins, and Cardiovascular Risk Factors:

Sophie Domingues-Montanari, Isaac Subirana, Marta Tomás, Jaume Marrugat, and Mariano Sentí

Association between ESR2 Genetic Variants and Risk of Myocardial Infarction
Clin Chem 2008 54: 1183-1189. Published online May 16, 2008; 10.1373/clinchem.2007.102400 [Abstract] [Full Text] [PDF]  

John H. Page, Jing Ma, Kathryn M. Rexrode, Nader Rifai, JoAnn E. Manson, and Susan E. Hankinson

Plasma Dehydroepiandrosterone and Risk of Myocardial Infarction in Women
Clin Chem 2008 54: 1190-1196. Published online May 1, 2008; 10.1373/clinchem.2007.099291 [Abstract] [Full Text] [PDF]  

General Clinical Chemistry:

Hendrick E. van Deventer, Jaya A. George, Janice E. Paiker, Piet J. Becker, and Ivor J. Katz

Estimating Glomerular Filtration Rate in Black South Africans by Use of the Modification of Diet in Renal Disease and Cockcroft-Gault Equations
Clin Chem 2008 54: 1197-1202. Published online May 16, 2008; 10.1373/clinchem.2007.099085 [Abstract] [Full Text] [PDF] Supplemental Data  

Evidence-Based Laboratory Medicine and Test Utilization:

Kelly E. McGowan, Martha E. Lyon, and J. Decker Butzner

Celiac Disease and IgA Deficiency: Complications of Serological Testing Approaches Encountered in the Clinic
Clin Chem 2008 54: 1203-1209. Published online May 16, 2008; 10.1373/clinchem.2008.103606 [Abstract] [Full Text] [PDF] Supplemental Data  

Marjorie G. Garrod, Ralph Green, Lindsay H. Allen, Dan M. Mungas, William J. Jagust, Mary N. Haan, and Joshua W. Miller

Fraction of Total Plasma Vitamin B12 Bound to Transcobalamin Correlates with Cognitive Function in Elderly Latinos with Depressive Symptoms
Clin Chem 2008 54: 1210-1217. Published online May 1, 2008; 10.1373/clinchem.2007.102632 [Abstract] [Full Text] [PDF]  

Automation and Analytical Techniques:

Sigrun M. Gustafsdottir, Stefan Wennström, Simon Fredriksson, Edith Schallmeiner, Andrew D. Hamilton, Said M. Sebti, and Ulf Landegren

Use of Proximity Ligation to Screen for Inhibitors of Interactions between Vascular Endothelial Growth Factor A and Its Receptors
Clin Chem 2008 54: 1218-1225. Published online May 22, 2008; 10.1373/clinchem.2007.099424 [Abstract] [Full Text] [PDF]  

Hemostasis and Thrombosis:

Willem M. Lijfering, Herman G. Sprenger, Rita R. Georg, Piet A. van der Meulen, and Jan van der Meer

Relationship between Progression to AIDS and Thrombophilic Abnormalities in HIV Infection
Clin Chem 2008 54: 1226-1233. Published online May 1, 2008; 10.1373/clinchem.2008.103614 [Abstract] [Full Text] [PDF]  

Brief Communication:

Kerstin Kurz, Evangelos Giannitsis, Joerg Zehelein, and Hugo A. Katus

Highly Sensitive Cardiac Troponin T Values Remain Constant after Brief Exercise- or Pharmacologic-Induced Reversible Myocardial Ischemia
Clin Chem 2008 54: 1234-1238. [Abstract] [Full Text] [PDF] Supplemental Data  

Clinical Case Studies:

George van der Watt, David Haarburger, and Peter Berman

Euthyroid Patient with Elevated Serum Free Thyroxine
Clin Chem 2008 54: 1239-1241. [Extract] [Full Text] [PDF]  

Mark D. Kellogg, Terence C. Law, Stephen Huang, and Nader Rifai

A Girl with Goiter and Inappropriate Thyroid-Stimulating Hormone Secretion
Clin Chem 2008 54: 1241-1244. [Extract] [Full Text] [PDF]  

Larry J. Kricka

Commentary
Clin Chem 2008 54: 1245. [Extract] [Full Text] [PDF]  

Kenneth D. Burman

Commentary
Clin Chem 2008 54: 1246. [Extract] [Full Text] [PDF]  

Citation Classic:

Hans Lilja

Testing New PSA Subforms to Enhance the Accuracy of Predicting Cancer Risk and Disease Outcome in Prostate Cancer
Clin Chem 2008 54: 1248-1249. [Extract] [Full Text] [PDF]  

Letters to the Editor:

Julian Gordon and Gerd Michel

Analytical Sensitivity Limits for Lateral Flow Immunoassays
Clin Chem 2008 54: 1250-1251. [Extract] [Full Text] [PDF] Data Supplement  

Angineh Gharapetian, Daniel T. Holmes, Nadine Urquhart, and Frances Rosenberg

Dehydrogenase Interference with Enzymatic Ethanol Assays: Forgotten but Not Gone
Clin Chem 2008 54: 1251-1252. [Extract] [Full Text] [PDF] Supplemental Data  

Michael Mannstadt, Carol Lorente, and Harald Jüppner

Rapid Detection of Intact FGF-23 in Tumor Tissue from Patients with Oncogenic Osteomalacia
Clin Chem 2008 54: 1252-1254. [Extract] [Full Text] [PDF]  

Jonna Skov Madsen, Mads Nybo, Erik Magid, Jørgen Hilden, Nete Hornung, Torben Bjerregaard Larsen, Lone Jørgensen, and Per Erik Jørgensen

More Studies on Outcomes Using Biochemical Diagnostic Tests Are Needed: Findings from the Danish Society of Clinical Biochemistry
Clin Chem 2008 54: 1254-1256. [Extract] [Full Text] [PDF]  

Robert H. Bateman, Brian N. Green, and Michael Morris

Electrospray Ionization Mass Spectrometric Analysis of the Globin Chains in Hemoglobin Heterozygotes Can Detect the Variants HbC, D, and E
Clin Chem 2008 54: 1256-1257. [Extract] [Full Text] [PDF]  

Liesbeth Vynckier, Veronique Stove, and Joris R. Delanghe

Macromolecular Cystatin C Can Be a Caveat for Estimating Glomerular Filtration Rate in Biliary Obstruction
Clin Chem 2008 54: 1257-1259. [Extract] [Full Text] [PDF]  

Book, Software and Website Reviews:

Anthony Kurec

The Hitchhiker’s Guide to Self-Management & Leadership: Strategies for Success. Seven Steps to Overachieving in Business and Life, 2nd ed. Christopher S. Frings, PhD, CSP. Washington, DC: AACC Press, 2007, 106 pp., $25. ISBN 078-1-59425-069-9.
Clin Chem 2008 54: 1260. [Extract] [Full Text] [PDF]  

Corrections:

Corrections
Clin Chem 2008 54: 1261. [Extract] [Full Text] [PDF]  

Corrections
Clin Chem 2008 54: 1261. [Extract] [Full Text] [PDF]  

Clinical Chemist:

Robert Rej

CSI: Beethoven
Clin Chem 2008 54: 1262-1263. [Extract] [Full Text] [PDF]  

2008 AACC Award Recipients
Clin Chem 2008 54: 1263. [Extract] [Full Text] [PDF]  

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